Table 1 Demographics, clinical and laboratory characteristics
Aortic Stenosis vs. Controls | Aortic Stenosis | ||||||
|---|---|---|---|---|---|---|---|
Variable | Aortic stenosis (n = 38) | Controls (n = 31) | p Value | Normal LVM (n = 21) | Mildly LVM ↑ (n = 10) | Considerably LVM ↑ (n = 7) | p Value |
Age (mean ± SD) | 73 ± 9 | 69 ± 10 | 0,08 | 75 ± 5 | 70 ± 11 | 70 ± 15 | 0,31 |
Woman | 42% | 52% | 0,29 | 48% | 30% | 42% | 0,64 |
CAD | 66% | 45% | 0,07 | 52%# | 100%# | 57% | 0,03 # * |
Hx of MI | 10% | 36% | 0,01* | 5% | 20% | 14% | 0,41 |
Hx of CABG | 5% | 10% | 0,37 | 5% | 0% | 14% | 0,42 |
Diabetes mellitus | 34% | 20% | 0,15 | 27% | 40% | 43% | 0,72 |
Hypertension | 87% | 92% | 0,38 | 90% | 80% | 85% | 0,72 |
Hyperlipidemia | 53% | 83% | 0,01* | 47% | 60% | 57% | 0,8 |
Smoking | 16% | 57% | 0,001 | 14% | 10% | 29% | 0,56 |
ACE-inhibitor | 66% | 58% | 0,34 | 62% | 60% | 85% | 0,48 |
β-Blockers | 76% | 74% | 0,52 | 81% | 70% | 71% | 0,75 |
Statins | 50% | 64% | 0,18 | 38% | 50% | 85% | 0,41 |
CRP (mg/dl) | 0,94 | 0,99 | 0,91 | 1,1 | 0,6 | 1,1 | 0,85 |
NTproBNP (pg/ml) | n.d. | n.d. | 1635# | 2015# | 5988 | 0,05 # * | |
Creatinine (mg/dl) | 1,08 | 1,07 | 0,92 | 1,07 | 1,08 | 1,09 | 0,99 |