Table 1 Study population characteristics (n = 20)
Age (years) | 50 ± 8 |
Men/Women | 9 (45%)/11 (55%) |
Weight (kg) | 141 ± 21 |
BMI (kg/m2) | 50 ± 5 |
Known CAD | 1 (5%) |
Risk factors for CAD | |
Systemic hypertension | 15 (75%) |
Diabetes mellitus | 13 (65%) |
Smoking (active or past) | 8 (40%) |
Dyslipidemia | 13 (65%) |
Positive family history for CAD | 3 (15%) |
Sleep apnea | 15 (75%) |
Abnormal resting ECG | 6 (30%) |
Medications | |
Aspirin | 10 (50%) |
Beta-blockers | 5 (25%) |
Calcium channel blockers | 5 (25%) |
ACEI/ARB | 12 (60%) |
Statins | 6 (30%) |
Fibrates | 2 (10%) |
Ezetimide | 2 (10%) |
Nitrates | 1 (5%) |
Diuretics | 8 (40%) |
Oral hypoglycaemic agents | 9 (45%) |
Insulin | 5 (25%) |
Baseline blood chemistry | |
Fasting blood glucose (mmol/L) | 7.4 ± 3,5 |
HbA1c (%) | 6.9 ± 1.5 |
Total cholesterol (mmol/L) | 4.7 ± 1.4 |
LDL-cholesterol (mmol/L) | 3.1 ± 1.2 |
HDL-cholesterol (mmol/L) | 1.3 ± 0.2 |
Total cholesterol/HDL cholesterol | 3.7 ± 1.3 |
Triglycerides (mmol/L) | 2.0 ± 1.3 |