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Table 5 (Comparison of influence of therapy on the 3 categories of patients)

From: Outcome of coronary plaque burden: a 10-year follow-up of aggressive medical management

PARAMETER Patients untreated for Hypercholesterolaemia Patients on Statins alone Patients on Statins + Risk Factor Modification (RFM)
Change in Total Cholesterol after intervention Nil Nil Nil
Change in HDL Cholesterol after intervention Nil Nil Nil
Change in LDL Cholesterol after intervention Nil Nil Nil
Change in Triglycerides after intervention Nil Nil Nil
Change in Calcium score with intervention Nil 52/70 patients (= 74.3%) progressed in Calcium score on Statins alone
18/23 patients (= 78.3%) regressed in Calcium score on Statins
18/70 patients (= 25.7%) progressed in calcium score on Statins + RFM
5/23 patients (= 21.7%) regressed in calcium score on Statins + RFM
PARAMETERS Patients untreated for Hypercholesterolaemia Rising Ca score on statins alone Decreasing Ca score on statins alone Rising Ca score on statins + RFM Decreasing Ca score on statins + RFM
No. of Patients 7 52 out of 70 patients (= 74.3%) 18 out of 23 patients (= 78.3%) 18 out of 70 patients (= 25.7%) 5 out of 23 patients (= 21.7%)
Calcium score Zero at baseline and zero on follow-up From a mean calcium score of 111.7 to 301.2 (+169.7%) From a mean calcium score of 276.2 to 194.9 (-29.4%) From a mean calcium score of 89.17 to 147.6 (+65.5%) From a mean calcium score of 26.7 to 19.5 (-27%)