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Table 5 (Comparison of influence of therapy on the 3 categories of patients)

From: Outcome of coronary plaque burden: a 10-year follow-up of aggressive medical management

PARAMETER

Patients untreated for Hypercholesterolaemia

Patients on Statins alone

Patients on Statins + Risk Factor Modification (RFM)

Change in Total Cholesterol after intervention

Nil

Nil

Nil

Change in HDL Cholesterol after intervention

Nil

Nil

Nil

Change in LDL Cholesterol after intervention

Nil

Nil

Nil

Change in Triglycerides after intervention

Nil

Nil

Nil

Change in Calcium score with intervention

Nil

52/70 patients (= 74.3%) progressed in Calcium score on Statins alone

18/23 patients (= 78.3%) regressed in Calcium score on Statins

18/70 patients (= 25.7%) progressed in calcium score on Statins + RFM

5/23 patients (= 21.7%) regressed in calcium score on Statins + RFM

PARAMETERS

Patients untreated for Hypercholesterolaemia

Rising Ca score on statins alone

Decreasing Ca score on statins alone

Rising Ca score on statins + RFM

Decreasing Ca score on statins + RFM

No. of Patients

7

52 out of 70 patients (= 74.3%)

18 out of 23 patients (= 78.3%)

18 out of 70 patients (= 25.7%)

5 out of 23 patients (= 21.7%)

Calcium score

Zero at baseline and zero on follow-up

From a mean calcium score of 111.7 to 301.2 (+169.7%)

From a mean calcium score of 276.2 to 194.9 (-29.4%)

From a mean calcium score of 89.17 to 147.6 (+65.5%)

From a mean calcium score of 26.7 to 19.5 (-27%)