Pre-implant right ventricular function might be an important predictor of the response to cardiac resynchronization therapy

Table 2 Clinical and Echocardiographic (conventional, 3D and TDI) changes from pre-implantation to four weeks after CRT implantation

Variable	Pre- implantation	Four weeks after CRT-implantation	p-value
QRS, ms	155 ± 20	162 ± 29	n.s.
NT-proBNP, pg/ml	2925 ± 2611	3290 ± 3545	n.s.
Minnesota-score, median(range)	49 (11-90)	30 (1-69)	0.0004
NYHA-class, median(range)	3 (2-4)	2 (1-3)	0.0064
LV EDd, mm	67.6 ± 9.2	67.4 ± 8.9	n.s.
LV ESd, mm	59.2 ± 10.1	59.3 ± 9.9	n.s.
MR, 0-4, median(range)	1.5(0.5-2.5)	1.0(0.0-2.5)	0.063
LV EDV, ml	226 ± 71	211 ± 64	0.020
LV ESV, ml	169 ± 64	163 ± 59	n.s.
EF, %	24 ± 7	24 ± 8	n.s.
Ts septum-lateral, ms	60 ± 31	52 ± 44	n.s.
LV TT, mm	3.1 ± 1.2	3.9 ± 1.5	0.038
LV SMV, cm/s	2.2 ± 0.4	2.6 ± 0.9	0.045
RV TT, mm	8.8 ± 4.8	9.4 ± 3.7	n.s.
RV SMV, cm/s	6.2 ± 2.6	6.5 ± 2.6	n.s.

Mean ± SD unless otherwise stated. MR = mitral regurgitation, Ts = dyssynchrony, SMV = systolic maximal velocity, LV EDd = left ventricular end diastolic diameter, LV ESd = left ventricular end systolic diameter, EF = ejection fraction. EDV = end diastolic volume, ESV = end systolic volume, TT = tissue tracking, RV = right ventricular.

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