|
Non-inducible
| |
Inducible
| |
---|
|
Baseline
|
Pilsicainide
| |
Baseline
|
Pilsicainide
| |
---|
HR (bpm)
|
64.2 ± 8.2
|
66.9 ± 6.9
| |
66.0 ± 14.1
|
67.7 ± 10.5
| |
PR (ms)
|
157 ± 20.6
|
183 ± 44.4
|
**
|
162 ± 14.9
|
211.6 ± 24.7
|
** ✝
|
QRS (ms)
|
96.5 ± 12.7
|
121.2 ± 12.8
|
**
|
106.4 ± 8.4
|
129.1 ± 11
|
**
|
QTc (ms)
|
399.2 ± 18.6
|
426 ± 21.5
|
**
|
401.6 ± 17.2
|
429.9 ± 13.9
|
**
|
E/A
|
1.33 ± 0.53
|
1.71 ± 0.54
|
**
|
1.56 ± 0.6
|
2.02 ± 0.91
|
**
|
DcT (ms)
|
205.0 ± 37.7
|
177.9 ± 29.9
|
**
|
187.6 ± 28.4
|
172.6 ± 29.2
| |
RV ET (ms)
|
315.3 ± 26.6
|
322.9 ± 28.6
| |
326.8 ± 30.9
|
319.2 ± 28.0
| |
LV ET (ms)
|
298.6 ± 20.7
|
301.5 ± 23.1
| |
304.5 ± 28.6
|
289.4 ± 17.8
| |
RV ICT (ms)
|
73.8 ± 16.5
|
76.1 ± 19.2
| |
71.5 ± 6.6
|
89.35 ± 13.4
|
** ✝
|
LV ICT (ms)
|
75.0 ± 21.2
|
84.9 ± 26.5
|
*
|
62.6 ± 5.8
|
72.9 ± 11.6
|
**
|
RV TEI index
|
0.19 ± 0.06
|
0.19 ± 0.05
| |
0.19 ± 0.09
|
0.27 ± 0.11
|
* ✝
|
LV TEI index
|
0.31 ± 0.08
|
0.34 ± 0.08
| |
0.30 ± 0.10
|
0.45 ± 0.10
|
** ✝✝
|
- Values are expressed as means ± SD. *P < .05 and **P < .01 vs corresponding value at baseline.
- ✝P < .05 and ✝✝P < .01 vs corresponding value in Non-inducible. HR, heart rate; E/A, ratio of early to late transmitral inflow velocity; DcT, deceleration time of early transmitral inflow velocity; ET, ejection time; ICT, isovolumic contraction time