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Table 1 Basal characteristic of overall population according to MR grade groups

From: The beneficial effects of TAVI in mitral insufficiency

 

All

Preoperative MR

Preoperative MR

p value

Grade 3–4

Grade 1–2

Patients

165

28

137

 

Demographics

Males

74 (44.8 %)

19 (67.9 %)

55 (40.1 %)

0.01

Mean Age (years)

80.2 ± 5.6

81 ± 5.2

79.9 ± 5.6

0.38

Weight (kg)

67.1 ± 10.8

71.6 ± 7.2

66.2 ± 11.1

0.01

Height (m)

1.62 ± 0.07

1.67 ± 0.05

1.61 ± 0.08

0.0005

Body surface area (m2)

1.7 ± 0.2

1.81 ± 0.08

1.69 ± 0.16

0.0005

Ejection Fraction (%)

51 ± 9.3

39.8 ± 7.5

53.2 ± 7.9

<0.0001

Aortic valve

Peak gradient (mmHg)

75.5 ± 17.5

63.8 ± 20.8

77.9 ± 15.7

<0.0001

Mean gradient (mmHg)

44.8 ± 8.2

39.5 ± 10.5

45.8 ± 7.2

0.0002

Aortic valve area (cm2)

0.59 ± 0.9

0.58 ± 0.08

0.6 ± 0.1

0.34

Mitral valve

MR mechanism

 Degenerative

118 (71.5 %)

7 (25 %)

111 (81 %)

<0.0001

 Functional

47 (28.5 %)

21 (75 %)

26 (19 %)

<0.0001

Leaflets disease

 Calcifications

55 (33.3 %)

2 (7.1 %)

53 (38.7 %)

0.0008

 Thickening

63 (38.2 %)

5 (17.9 %)

58 (42.3 %)

0.02

 Prolapse

7 (4.2 %)

2 (7.1 %)

5 (3.6 %)

0.33

Mitral regurgitation [14]

1.9 ± 0.7

3.1 ± 0.3

1.6 ± 0.5

<0.0001

 MR grade I

54 (32.7 %)

54 (192.9 %)

0 (0 %)

n.c

 MR grade II

83 (50.3 %)

83 (296.4 %)

0 (0 %)

n.c.

 MR grade III

25 (15.2 %)

0 (0 %)

25 (18.2 %)

n.c.

 MR grade IV

3 (1.8 %)

0 (0 %)

3 (2.2 %)

n.c.

EROA (mm2)

24.9 ± 8

38.5 ± 6.7

22.1 ± 4.7

<0.0001

Vena contracta (mm)

36.1 ± 11.8

55.4 ± 9.4

32.1 ± .7.5

<0.0001

Regurgitant volume (ml)

35.1 ± 10.2

50.8 ± 7

31.9 ± 7.3

<0.0001

Regurgitant fraction (%)

33.6 ± 9.9

48.6 ± 6.4

30.4 ± 7.2

<0.0001

LA volume (ml)

64.2 ± 14.3

79.6 ± 17.7

61 ± 11.1

<0.0001

Procedure

Prosthesis model

 Corevalve

114 (69.1 %)

19 (67.9 %)

95 (69.3 %)

0.99

 Sapien

51 (30.9 %)

9 (32.1 %)

42 (30.7 %)

0.99

Valve size (mm)

26.8 ± 2.5

27.8 ± 2.3

26.6 ± 2.4

0.02