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Table 1 Clinical characteristics according to aPWV groups

From: Left ventricular twist mechanics and its relation with aortic stiffness in chronic kidney disease patients without overt cardiovascular disease

 

Normal PWV <10 m/s

Increased PWV ≥ 10 m/s

p-value

n = 64

n = 42

Clinical demographics

   

 Age

51.2 ± 14

63 ± 12

<0.001*

 Male gender (%)

45.4

41.2

0.455

 BSA (g/m2)

1.88 ± 0.21

1.87 ± 0.22

0.906

Cardiovascular risk factors

   

 BMI (g/m2)

26.9 ± 5

27.8 ± 5.1

0.367

 eGFR (mL/min/1.73 m2)

48.95 ± 20.1

30.5 ± 15.4

<0.001*

 Systolic BP (mmHg)

127.2 ± 20.4

140.5 ± 18.5

0.01*

 Diastolic BP (mmHg)

77.9 ± 10.6

79.5 ± 10.5

0.451

 Diabetes (%)

20.3

71

<0.001*

 Hypertension (%)

62.5

82.8

<0.001*

 Family history of IHD (%)

29.7

26.8

0.755

Smoking status (%) Current

   

 Current

6.3

9.8

0.295

 Ex

9.4

9.8

 

 Never

45.3

34.1

 

Medication

   

 Aspirin (%)

28

37

0.367

 Clopidogrel (%)

2

7

0.135

 ACE-I (%)

34

69

<0.001*

 ARBs (%)

53

51

0.858

 Beta-blockers (%)

16

22

0.416

 CCB dihydropyridine (%)

25

38

0.151

 Loop diuretic (%)

22

34

0.112

 Thiazide diuretic (%)

2

10

0.06

 Any antihypertensive (%)

40.1

87.2

 

 Statins (%)

61

80

0.110

 Prednisolone (%)

22

10

0.125

 Metformin (%)

9

18

0.081

 Gliclazide (%)

9

12

0.649

 Insulin (%)

8

41

<0.001*

  1. BSA body surface area; BMI body mass index; GFR glomerular filtration rate, CKD chronic kidney disease; BP blood pressure; ARB angiotensin II receptor blocker; CCB calcium channel blocker; IHD ischemic heart disease; ACE-I angiotensin-converting enzyme inhibitor; ARB angiotensin II receptor blocker
  2. *Statistically significant difference between the two groups