Table 2 Unadjusted and multivariable-adjusted Cox proportionate hazard models for composite outcomes (death and hospitalization for HF) by LVEF measured in-hospital (N = 445, no of events = 52)
Unadjusted cox proportional hazard model | ||
Variables | HR (95 % CI) | P-value |
LVEF/5 % decrease | 1.31 (1.20,1.45) | < 0.001 |
Age/10 years increase | 1.79 (1.44, 2.24) | < 0.001 |
Gender, Male | 1.37 (0.41, 1.32) | 0.23 |
White race (nonwhite race reference) | 1.13 (0.48, 2.65) | 0.77 |
Body Mass Index | 0.97 (0.92, 1.02) | 0.32 |
Time from onset of symptoms to treatment* | 0.98 (0.99, 1.00) | 0.33 |
Chief complaint on presentation | ||
Chest pain | 0.53 (0.23, 1.12) | 0.10 |
Out of Hospital ECG ST-Elevation | 0.84 (0.47, 1.50) | 0.55 |
ACI-TIPI Score | 1.02 (0.99, 1.04) | 0.12 |
Medical history | ||
CAD (MI, PCI or CABG) | 4.46 (2.47, 8.04) | < 0.001 |
Heart Failure | 3.56 (1.86, 6.79) | < 0.001 |
Diabetes | 1.88 (1.06, 3.34) | 0.03 |
Hypertension | 2.17 (1.12, 4.23) | 0.02 |
Stroke | 2.56 (1.20, 5.43) | 0.02 |
Multivariable adjusted cox proportional hazard models | ||
Variables | HR (95 % CI) | P value |
Outcome (Composite) | ||
LVEF/5 % lower (combined) | 1.26 (1.15, 1.38) | < 0.001 |
Age/10 years Increase | 1.73 (1.38, 2.18) | < 0.001 |
History of CAD (MI, PCI, or CABG) | 2.97 (1.62, 5.43) | < 0.001 |
Outcome (Death) | ||
LVEF/5 % lower (combined) | 1.18 (1.06, 1.32) | 0.002 |
Age/10 years Increase | 1.94 (1.47, 2.55) | <0.001 |
History of CAD (MI, PCI, or CABG) | 3.56 (1.69, 7.49) | < 0.001 |
Outcome (Hospitalization for HF) | ||
LVEF/5 % lower (combined) | 1.37 (1.18, 1.58) | < 0.001 |
Age/10 years Increase | 1.35 (0.95, 1.91) | 0.09 |
History of CAD (MI, PCI, or CABG) | 2.27 (0.93, 5.56) | 0.007 |