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Table 2 Unadjusted and multivariable-adjusted Cox proportionate hazard models for composite outcomes (death and hospitalization for HF) by LVEF measured in-hospital (N = 445, no of events = 52)

From: In-hospital measurement of left ventricular ejection fraction and one-year outcomes in acute coronary syndromes: results from the IMMEDIATE Trial

Unadjusted cox proportional hazard model   
Variables HR (95 % CI) P-value
LVEF/5 % decrease 1.31 (1.20,1.45) < 0.001
Age/10 years increase 1.79 (1.44, 2.24) < 0.001
Gender, Male 1.37 (0.41, 1.32) 0.23
White race (nonwhite race reference) 1.13 (0.48, 2.65) 0.77
Body Mass Index 0.97 (0.92, 1.02) 0.32
Time from onset of symptoms to treatment* 0.98 (0.99, 1.00) 0.33
Chief complaint on presentation   
 Chest pain 0.53 (0.23, 1.12) 0.10
 Out of Hospital ECG ST-Elevation 0.84 (0.47, 1.50) 0.55
 ACI-TIPI Score 1.02 (0.99, 1.04) 0.12
Medical history   
 CAD (MI, PCI or CABG) 4.46 (2.47, 8.04) < 0.001
 Heart Failure 3.56 (1.86, 6.79) < 0.001
 Diabetes 1.88 (1.06, 3.34) 0.03
 Hypertension 2.17 (1.12, 4.23) 0.02
 Stroke 2.56 (1.20, 5.43) 0.02
Multivariable adjusted cox proportional hazard models
 Variables HR (95 % CI) P value
Outcome (Composite)   
 LVEF/5 % lower (combined) 1.26 (1.15, 1.38) < 0.001
 Age/10 years Increase 1.73 (1.38, 2.18) < 0.001
 History of CAD (MI, PCI, or CABG) 2.97 (1.62, 5.43) < 0.001
Outcome (Death)   
 LVEF/5 % lower (combined) 1.18 (1.06, 1.32) 0.002
 Age/10 years Increase 1.94 (1.47, 2.55) <0.001
 History of CAD (MI, PCI, or CABG) 3.56 (1.69, 7.49) < 0.001
Outcome (Hospitalization for HF)   
 LVEF/5 % lower (combined) 1.37 (1.18, 1.58) < 0.001
 Age/10 years Increase 1.35 (0.95, 1.91) 0.09
 History of CAD (MI, PCI, or CABG) 2.27 (0.93, 5.56) 0.007