Control (n = 23) | VSD (n = 35) | p values | ||
---|---|---|---|---|
Sex (male/female) | 11/12 | 20/15 | n.s. | |
Age (y) | 2.5 ± 1.6 | 2.3 ± 1.5 | n.s. | |
Weight (kg) | 13.8 ± 3.3 | 11.4 ± 4.1 | 0.0224 | |
Height (cm) | 91.1 ± 7.1 | 88.7 ± 8.1 | n.s. | |
Body surface area (m2) | 0.58 ± 0.07 | 0.53 ± 0.08 | 0.0177 | |
Heart rate (bpm) | 90 ± 12 | 92 ± 17 | n.s. | |
QRS duration (msec) | 87 ± 6 | 89 ± 13 | n.s. | |
Systolic blood pressure (mmHg) | 80 ± 7 | 77 ± 6 | n.s. | |
Diastolic blood pressure (mmHg) | 46 ± 6 | 45 ± 6 | n.s. | |
LVEDD (mm) | 25.8 ± 3.1 | 29.2 ± 4.4 | 0.0022 | |
LVFS (%) | 32.6 ± 5.9 | 38.7 ± 6.1 | 0.0004 | |
LVEF (%) | 63.4 ± 5.6 | 69.3 ± 6.2 | 0.0005 | |
Qp/Qs | - | 2.04 ± 0.92 | - | |
RVSP (mmHg) | - | 35.4 ± 13.0 | - | |
RVEDP (mmHg) | - | 7.6 ± 2.1 | - | |
RVEF (%) | - | 53.0 ± 9.1 | - | |
SPAP (mmHg) | - | 29.0 ± 9.9 | - | |
DPAP (mmHg) | - | 11.5 ± 3.3 | - | |
MPAP (mmHg) | - | 19.7 ± 6.2 | - | |
PAPP (mmHg) | - | 17.5 ± 8.0 | - | |
PVRi (Wood U∙m2) | - | 1.44 ± 0.8 | - | |
PASV (ml/m2) | - | 62.7 ± 20.7 | - | |
Transmitral flow (m/sec) | E | 1.05 ± 0.17 | 1.11 ± 0.19 | n.s. |
A | 0.41 ± 0.07 | 0.51 ± 0.17 | 0.0099 | |
Transtricuspid flow (m/sec) | E | 0.64 ± 0.12 | 0.49 ± 0.18 | 0.0009 |
A | 0.29 ± 0.09 | 0.31 ± 0.13 | n.s. | |
Mitral annular motion (cm/sec) | s’ | 8.4 ± 1.6 | 9.5 ± 2.7 | 0.0292 |
e’ | 14.6 ± 2.8 | 15.7 ± 2.9 | n.s. | |
a’ | 5.0 ± 2.3 | 6.1 ± 2.4 | n.s. | |
Tricuspid annular motion (cm/sec) | s’ | 12.5 ± 2.2 | 13.6 ± 1.8 | 0.0418 |
e’ | 14.2 ± 2.3 | 12.7 ± 3.2 | n.s. | |
a’ | 6.6 ± 2.3 | 6.5 ± 2.1 | n.s. |