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Table 4 Effect of cardiac shock wave therapy in human controlled studies: clinical and quality of life parameters

From: Cardiac shock-wave therapy in the treatment of coronary artery disease: systematic review and meta-analysis

  

 Period

CCS angina class

Nitroglycerine consumption

NYHA class

Seattle angina questionnaire

P. Yang 2013 [79]

Test group (N=14)

Baseline

2.0 (1.0, 3.0)

2.0 (0.0, 3.0)

2.0 (1.0, 2.0)

73.5 (60.5, 81.0)

Post treatment

1.0 (1.0, 2.0)*

1.0 (0.0, 2.0)

1.0 (1.0, 1.0)*

82.0 (74.5, 88.0)*

Placebo group (N=11)

Baseline

2.0 (1.0, 3.0)

2.0 (1.0, 3.0)

1.0 (1.0, 2.0)

73.0 (63.0, 80.0)

Post treatment

2.0 (1.0, 2.0)

2.0 (0.0, 2.0)

2.0 (1.0, 2.0)

78.0 (69.0, 85.0)

Y. Wang 2012 [24]

I group (standard treatment) (N=20)

Baseline

2 (1, 2)

1 (0, 2)

1.5 (1, 3)

64.9±11.72

Post treatment

1 (1, 1)*

0 (0, 1)

1 (1, 1)

75.0±10.45*

II group (modified treatment) (N=21)

Baseline

3 (2, 3)

2 (0, 3)

2 (1, 2.5)

67.9±13.0

Post treatment

2 (1, 2)

0 (0, 1)

1 (1, 1)

76.14±12.28

Control group (N=14)

Baseline

2 (2, 3)

1 (0, 4)

2 (1, 3)

63.21±11.89

Post treatment

2 (1, 2.3)

0 (0, 2)

1 (1, 2.3)

60.14±12.82

P. Yang 2012 [76]

Test group (N=25)

Baseline

2.72±0.46

2.35±0.86

2.16±0.69

65.96±11.78

Post treatment

1.46±0.58*

1.0±0.73*

1.48±0.65*

76.4±11.78*

Placebo group (N=20)

Baseline

    

Post treatment

No significant changes

No significant changes

No significant changes

No significant changes

S. Nirala 2016 [73]

Test group (N=41)

Baseline

2.21±0.85

1.34±1.35

1.85±0.96

66.34±12.34

Post treatment

1.14±0.57

0.21±0.82*

1.04±0.49**

79.92±25.14**

Control group (N=11)

Baseline

1.81±0.75

1.36±1.62

1.36±0.67

84±7.61

Post treatment

2.18±0.75

2±1.18

2.09±0.94

72.72±12.33

Y. Kikuchi 2010 [31]

Test group (N=8)

Baseline

3.0

4.0

-

-

Post treatment

2.25*

1.0*

-

-

Placebo group (N=8)

Baseline

2.75

4.0

-

-

Post treatment

2.75

3.0*

-

-

W.H. Kazmi 2012 [71]

Test group (N=43)

Baseline

2.63±0.7

-

2.48±0.6

-

Post treatment

1.95±0.8**

-

1.95±0.5**

-

Control group (N=43)

Baseline

2.63±0.7

-

2.48±0.6

-

Post treatment

2.63±0.7

-

2.46±0.6

-

G. Alunni 2014 [72]

Test group (N=43)

Baseline

2.67±0.75

26(60.5%)

2.51±0.74

-

Post treatment

1.33±0.57**

9 (20%)*

1.23±0.42**

-

Control group (N=29)

Baseline

2.52±0.78

18 (41%)*

2.32±0.79

-

Post treatment

1.92±0.69

13 (44.8%)*

1.73±0.59

-

  1. CCS Canadian Cardiovascular Society Angina Class, nitroglycerine consumption is expressed as number of tablets per day, NYHA New York Heart Association class, * = p<0.05 compared to baseline, ** = p<0.001 compared to baseline