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Table 2 Classical dyssynchrony 2D–echocardiographic parameters and 3D- echocardiographic integral-based indicators of longitudinal strain

From: Pilot study using 3D–longitudinal strain computation in a multi-parametric approach for best selecting responders to cardiac resynchronization therapy

  All patients (n = 48) CRT Responders (n = 34, 71%) CRT Nonresponders (n = 14, 29%) p Value
Atrioventricular dyssynchrony, n (%) 23 (48%) 16 (47%) 7 (50%) 0.853
IVMD >40 ms, n (%) 38 (79%) 31 (91%) 7 (50%) 0.003*
LVPEI (ms) 171 ± 27 175 ± 27 164 ± 28 0.189
DTI septo-lateral delay (ms) 110 [74;161] 114 [74;189] 93 [72;117] 0.162
Septal Flash, n (%) 30 (63%) 27 (79%) 3 (21%) 0.001*
Mean strain peak (%) −10.2 [−11.6;-9.2] −10.6 [−11.7;-9.6] −9.7 [−11.3;-8.4] 0.302
SDtpeak (ms) 104 [80;123] 101 [80;123] 107 [66;121] 0.626
Mean IL,peak (%.s-1) 1.68 ± 0.59 1.80 ± 0.62 1.39 ± 0.41 0.029*
Mean I^avc (%.s−1) 0.62 [0.34;0.90] 0.76 [0.44;0.92] 0.45 [0.24;0.77] 0.129
SDIL,peak (%.s−1) 1.09 [0.82;1.32] 1.18 [0.96;1.35] 0.83 [0.55;0.99] 0.007*
SDIL,avc (%.s-1) 0.85 ± 0.37 0.90 ± 0.35 0.72 ± 0.39 0.125
DiffInt (%.s-1) 0.57 ± 0.5 0.61 ± 0.47 0.47 ± 0.58 0.360
MSDI (ms) 0.35 ± 0.16 0.37 ± 0.16 0.29 ± 0.14 0.106
  1. Data are presented as n (%), mean ± SD, median [IQR]. DiffInt average of 17 LV segments of the difference between IL,avc and IL,peak for each 17 LV segments, DTI doppler tissue imaging, LVPEI left ventricular pre-ejection interval, I L,avc integrals of longitudinal strain signals for each 17 LV segments from the beginning of the cardiac cycle (QRS onset) to the instant of aortic valve closure, I L,peak integrals of longitudinal strain signals for each 17 LV segments from the beginning of the cardiac cycle (QRS onset) to the instant of the corresponding longitudinal strain peak, IVMD interventricular mechanical delay, MSDI Maximal Difference between Strain peak Instants, SD standard deviation, SDI L , peak standard deviation of the integrals of strain signals I L,peak of 17 LV segments, SDI L,avc standard deviation of the integrals of strain signals I L,avc of 17 LV segments, t peak time to strain peak. * p Value <0,05