Table 1 Regensburg registry and other published trials and registries including patients treated by the MitraClip system
Regensburg | GRASP [17] | TRAMI [19] | MitraSWISS [18] | Pilot Registry [21]a | ACCESS-EU [20] | EVEREST-II [1] | |
|---|---|---|---|---|---|---|---|
Year of publication | 2016 | 2016 | 2014 | 2014 | 2013 | 2011 | |
Participants | 102 | 180 | 749 | 74 | 628 | 567 | 184 |
Female [%] | 42.2 | 38.3 | 38.6 | 27 | 36.9 | 36.2 | 38 |
Age [years] | 77.0 ± 5.8 | 71.6 ± 9.8 | 76 (10)b | 72 ± 12 | 74.2 ± 9.7 | 73.7 ± 9.6 | 67.3 ± 12.8 |
MR grade III/IV [%] | 100 | – | 93.8 | 100 | 86.1c | 97.7 | 96 |
DMR [%] | 28.4 | 18.3 | 27.8 | 38 | 22.8 | 20.6 | 74 |
FMR [%] | 71.6 | 81.7 | 71.3 | 62 | 72.0 | 69.3 | 27 |
NYHA III/IV [%] | 75.5 | 81.1 | 89 | – | 85.5 | 84.9 | 52 |
EuroScore II | 5.1 ± 5.9 | 7.6 ± 6.4 | – | – | – | – | – |
LogEuroScore [%] | 26.6 ± 18.0 | – | 20 (19)f | 21 ± 17 | 20.4 ± 16.7 | 23.0 ± 18.3 | – |
Regurgitant orifice area [cm2] | 0.40 ± 0.18 | – | – | – | 0.43 ± 0.16 | – | 0.56 ± 0.38 |