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Table 4 Effect of PMVR on mitral regurgitation, 6-min walk and LV remodelling

From: 3D vena contracta area after MitraClip© procedure: precise quantification of residual mitral regurgitation and identification of prognostic information

  Before PMVR After PMVR p-value
MR grade median (P25;P75) 4 (3.5;4.0) 1 (0.5;1.5) < 0.001
6 min walk [m] 257.5 ± 82.5 295.7 ± 96.3 < 0.01
VCA (3D) [cm2] median (P25;P75) 0.89 (0.65;1.33) 0.17 (0.09;0.37) < 0.0001
NT-proBNP [pg/ml] median(P25;75) 3618 (1619;5782) 3247 (2273;4693) 0.954
LV end-diastolic volume [ml/m2] 85.0 ± 26.5 79.4 ± 23.2 0.17
LV end-systolic volume [ml/m2] 49.8 ± 22.2 44.7 ± 17.4 0.11
LV ejection fraction [%] 42.5 ± 12.5 43.6 ± 10.1 0.51
  1. PMVR decreased mitral regurgitation and improved six-minute walking distance in a follow-up examination 4 weeks after the intervention. NT-proBNP and left-ventricular volumes and ejection fraction remained unchanged. Shown are mean ± standard deviation, if not indicated otherwise
  2. PMVR percutaneous mitral valve repair, LV left ventricular, MR mitral regurgitation, VCA (3D) vena contracta area determined by direct planimetry in a 3D–coulor Doppler full volume