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Table 3 Comparison of clinical and laboratory parameters at T0 and T6 in 41 RA patients

From: Prospective assessment of cardiovascular risk parameters in patients with rheumatoid arthritis

Variables

T0

T6

p

Clinical parameters

 DAS28

4.46 (1.15) (2.58–6.55)

3.33 (1.62) (0.66–6.88)

< 0.001

 M-HAQ

1.22 (0.52) (0–2.38)

1.31 (0.52) (0.25–2.38)

NS

 SBP, mmHg

123.8 (13.5) (90–160)

128.2 (13.6) (105–160)

NS

 BMI, kg/m2

24.8 (3.1) (18.6–29.95)

25.9 (3.4) (17.3–33.2)

0.002

 BMI > 30 kg/m2

0

5 (12.2)

0.03

 mSCORE, %

0.98 (2.1) (0–12)

2.99 (3.9) (0–18)

< 0.001

 High/very high CVD risk

2 (4.9)

10 (24.4)

0.01

 QTc, ms

341.9 (60.8) (187–446)

358.8 (59.5) (175–453)

NS

 cIMT, mm

0.76 (0.15) (0.43–1.2)

0.87 (0.21) (0.57–1.77)

< 0.001

 Carotid plaques presence

6 (14.6)

10 (24.4)

NS

Laboratory parameters

 NT-proBNP, pg/ml

88.9 (78) (12.2–351.2)

126.6 (186.5) (20.1–1175)

NS

 Glucose, mg/dl

89.3 (12.9) (54–120)

88.8 (14.5) (67–146)

NS

 TC, mg/dl

200.6 (42) (135–325)

206.3 (7.2) (101–318)

NS

 HDL-C, mg/dl

59.6 (14.2) (39–87)

60.3 (16.2) (30–102)

NS

 LDL-C, mg/dl

119.7 (36.2) (47–232)

120.8 (34.4) (41–190)

NS

 Triglycerides, mg/dl

106.5 (45.6) (43–214)

113.0 (53.5) (23–251)

NS

 AI (TC/HDL-C)

3.48 (0.81) (2.1–5.5)

3.53 (0.84) (2.0–5.8)

NS

 Serum creatinine, mg/dl

0.68 (0.15) (0.4–1.0)

0.66 (0.15) (0.4–1.0)

NS

 Serum uric acid, mg/dl

4.0 (0.9) (2.2–5.8)

4.5 (1.1) (2.5–7)

< 0.05

  1. Data are presented as mean (SD) (range) or number (%); AI atherogenic index, BMI body mass index, cIMT carotid intima media thickness, DAS28 disease activity score in 28 joints, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, M-HAQ modified health assessment questionnaire, NT-proBNP amino-terminal pro-brain natriuretic peptide, SBP systolic blood pressure, mSCORE modified Systemic Coronary Risk Evaluation, TC total cholesterol