Characteristic | Study population (n = 209) | AF recurrence – (n = 156) | AF recurrence + (n = 53) | P value |
---|---|---|---|---|
Age (y) | 56.1 ± 13.5 | 55.6 ± 13.5 | 57.4 ± 13.7 | 0.335 |
Male gender (n, %) | 130 (62.2) | 98(62.8) | 32 (60.4) | 0.753 |
Body mass index (kg/m2) | 26.5 ± 4.7 | 26.3 ± 4.5 | 27 ± 5.3 | 0.549 |
Tobacco use (n, %) | 52 (24.8) | 35 (28.8) | 17(32) | 0.281 |
Hypertension (n, %) | 86 (41.1) | 59 (37.8) | 27 (50.9) | 0.094 |
Diabetes (n, %) | 16 (7.7) | 9 (5.8) | 7 (13.2) | 0.079 |
Dyslipidemia (n, %) | 75 (35.9) | 55 (35.3) | 20 (37.7) | 0.747 |
History of heart failure (n, %) | 6 (2.9) | 4 (2.6) | 2 (3.8) | 0.651 |
Coronary artery disease (n, %) | 15 (7.2) | 10 (6.4) | 5 (9.4) | 0.464 |
History of TIAa/CVAb(n, %) | 19 (9.1) | 15 (9.6) | 4 (7.5) | 0.653 |
Failed drugs before ablation | ||||
Flecainide (n, %) | 46 (22) | 31(19.8) | 15(28.3) | 0.177 |
Propafenone(n, %) | 1(0.47) | 0 (0) | 1(1.8) | 0.083 |
Amiodarone(n, %) | 9 (4.3) | 6 (3.8) | 3 (5.6) | 0.555 |
Sotalol (n, %) | 24 (11.4) | 16 (10.2) | 8 (15) | 0.316 |
Metoprolol (n, %) | 2 (0.9) | 2 (1.2) | 0 (0) | 0.412 |
Bisoprolol (n, %) | 78 (37.3) | 57 (36.5) | 21 (39.6) | 0.620 |
Nebivolol (n, %) | 6 (3.8) | 5 (3.2) | 1 (1.8) | 0.632 |
ACEc inhibitors before ablation | 26 (12.4) | 20 (12.8) | 6 (11.3) | 0.809 |
ARBsd before ablation | 11 (5.2) | 9 (5.7) | 2 (3.7) | 0.592 |
Prior ablation | 39 (18.6) | 29 (18.5) | 10 (18.8) | 0.547 |
- AVNRTe | 13 (6.2) | 12 (7.7) | 1 (1.9) | 1.000 |
- Right atrial flutter | 13 (6.2) | 8 (5.1) | 5 (9.4) | 1.000 |
- AFf | 11 (5.3) | 8 (5.1) | 3 (5.7) | 1.000 |
- Other | 2 (1.0) | 1 (0.6) | 1 (1.9) | 1.000 |
CHA2DS2−VAsc score | 1.3 ± 1.4 | 1.2 ± 1.3 | 1.6 ± 1.7 | 0.134 |
Oral anticoagulation (n, %) | 60 (28.7) | 41 (26.3%) | 19 (35.8%) | 0.552 |
Aspirin (n, %) | 23 (11) | 17 (10.9) | 6 (11.3) | 0.874 |
Follow-up duration (months) | 16.8 ± 6.3 | 16.9 ± 5.7 | 16.6 ± 7.7 | 0.795 |
Re-do ablation | 31 (14.8) | 0 (0) | 31 (58.4) | – |
Medication in BPg | ||||
- Flecainide (n, %) | 62 (29.6) | 42 (26.9) | 20 (37.7) | 0.122 |
- Propafenone (n, %) | 2 (0.95) | 1 (0.64) | 1 (1.8) | 0.415 |
- Amiodarone (n, %) | 9 (4.3) | 6 (3.8) | 3 (5.6) | 0.561 |
- Sotalol (n, %) | 49 (23.4) | 34 (21.8) | 15 (28.3) | 0.310 |
- Metoprolol (n, %) | 1(0.4) | 1(0.6) | 0 (0) | 0.562 |
- Bisoprolol (n, %) | 111 (53.11) | 81 (51.9) | 30 (56.6) | 0.497 |
- Nebivolol (n, %) | 4 (1.9) | 4 (2.5) | 0 (0) | 0.241 |
- ACE inhibitors (n, %) | 27 (12.9) | 21 (13.4) | 6 (11.3) | 0.710 |
- ARBs (n, %) | 6 (2.8) | 6 | 0 | 0.150 |
Medication after BP | ||||
- Flecainide (n, %) | 25 (11.9) | 17 (10.8) | 8 (15) | 0.398 |
- Propafenone (n, %) | 2 (0.9) | 0 (0) | 2 (3.7) | 0.060 |
- Amiodarone (n, %) | 6 (2.8) | 3 (1.9) | 3 (5.6) | 0.154 |
- Sotalol (n, %) | 26 (12.4) | 18 (11.5) | 8 (15) | 0.478 |
- Metoprolol (n, %) | 1 (0.4) | 1(0.6) | 0 (0) | 0.562 |
- Bisoprolol (n, %) | 62 (29.6) | 50 (23.9) | 12 (22.6) | 0.211 |
- Nebivolol (n, %) | 6 (2.8) | 5 (3.2) | 1 (1.8) | 0.628 |
- ACE inhibitors (n, %) | 27 (12.9) | 21 (13.4) | 6 (11.3) | 0.710 |
- ARBs (n, %) | 6 (2.8) | 6 | 0 | 0.150 |
Recurrence in BP | 8 (3.8) | 0 (0) | 8(15.1) | < 0.001 |