The value of left ventricular strain–volume loops in predicting response to cardiac resynchronization therapy

Table 5 Analyses to identify baseline predictors of response to CRT

Variable	Univariate Analysis			Multivariate Analysis
Variable	OR	95% CI	P	OR	95% CI	P
Age	1.011	1.000–1.023	.054
Female	7.071	0.774–64.575	.083
QRS duration	1.004	0.976–1.032	.806
LBBB	1.417	0.310–6.470	.653
NYHA class III	1.800	0.380–8.535	.459
Nonischemic Etiology	1.633	0.383–6.968	.508
NT-proBNP	1.006	0.990–1.020	.340
hs CRP	1.001	1.000–1.070	.420
LVESD	1.009	0.998–1.020	.123
LVEDV	1.001	0.999–1.004	.330
LVEF	1.003	0.930–1.082	.939
GLS	0.892	0.809–0.984	.022	0.820	0.490–0.995	.190
GCS	0.922	0.852–0.997	.042	0.962	0.657–1.000	.660
TpPS-SD%	1.006	0.999–1.013	.112
Tmsv-SD%	1.007	1.002–1.015	.048	1.002	1.000–1.001	.120
SDI	0.978	0.958–0.999	.041	0.990	0.680–1.000	.240
MidLateral PS_Peak	0.818	0.697–0.960	.014	0.890	0.550–0.980	.150
Slope of MidLateral PS- Global volume loop	3.934	2.863–6.444	.016	2.880	1.230–6.700	.470
R²-S/D coupling of MidSeptal PS-Global volume loop	0.803	0.760–0.880	.009	0.878	0.810–0.930	.028
Slope of MidLateral PS-MidLateral volume loop	2.035	1.104–3.750	.023	1.796	0.980–3.000	.200

CI Confidence interval, GCS Global circumferential strain, GLS Global longitudinal strain, hs CRP High sensitive C-reactive protein, LVEDV Left ventricular end-diastolic volume, LVESD Left ventricular end-systolic diameter, NT-proBNP N-terminal of the prohormone brain natriuretic peptide, OR Odd ratio, PS Principal strain, SDI Strain delay index, Tmsv-SD% Standard deviation of time to minimum systolic volume corrected by R-R interval, TpPS-SD% Standard deviation of time to peak principal strain corrected by R-R interval

ISSN: 1476-7120