Table 1 Baseline characteristics of the study population, according to remodeling pattern at follow-up (Mean/Median and 95% confidence intervals, 95% CI)
Variable | Overall population n = 155 | No remodeling n = 121 | Remodeling n = 34 | p-value |
|---|---|---|---|---|
Age (yrs) | 62 [60–64] | 62 [59–65] | 61 [59–64] | 0.1 |
Male gender (%) | 128 (83%) | 95 (79%) | 33 (97%) | < 0.0001 |
Body mass index(kg/m2) | 26.2 [25.7–27.3] | 26.1 [25.4–28.7] | 26.2 [25.6–27.5] | 0.10 |
Body surface area (m2) | 1.9 [1.86–1.93] | 1.9 [1.8–2.0] | 1.9 [1.86–1.95] | 0.10 |
Coronary artery disease (%) | 72 (46%) | 51 (42%) | 21 (62%) | 0.10 |
Diabetes (%) | 28 (18%) | 22 (18%) | 6 (18%) | 0.010 |
Hypertension (%) | 63 (41%) | 50 (41%) | 13 (38%) | 0.003 |
HF history (%) | 87 (56%) | 64 (53%) | 23 (68%) | 0.10 |
CKDa (%) | 51 (33%) | 33 (27%) | 18 (53%) | 0.005 |
NYHA Class I | 47 (30%) | 43 (35.5%) | 4 (12%) | < 0.0001 |
NYHA Class II | 65 (42%) | 49 (40.5%) | 16 (47%) | 0.0001 |
NYHA Class III | 43 (28%) | 29 (24%) | 14 (41%) | 0.01 |
BNP (pg/mL) | 366 [289–428] | 289 [216–362] | 613 [451–775] | 0.0001 |
ICD baseline (%) | 64 (41%) | 40 (33%) | 24 (71%) | 0.30 |
CRT baseline (%) | 17 (11%) | 12 (10%) | 5 (15%) | 0.04 |
Mitral regurgitationb (%) | 51 (33%) | 33 (27%) | 18 (53%) | 0.005 |
Digoxin | 57 (36.7%) | 40 (33%) | 17 (50%) | 0.14 |
Diuretics | 134 (86%) | 100 (83%) | 34 (100%) | 0.18 |
ACE inhibitors or ARB | 147 (91%) | 116 (94%) | 31 (96%) | 0.47 |
MRI | 102 (66%) | 74 (61%) | 28 (82%) | 0.01 |
Beta-blockers | 109 (70%) | 75 (62%) | 34 (100%) | 0.35 |