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Table 3 Univariate and multivariate predictors of adverse left ventricular remodeling

From: The assessment of pressure-volume relationship during exercise stress echocardiography predicts left ventricular remodeling and eccentric hypertrophy in patients with chronic heart failure

Variable

Univariate analysis OR [95% CI]

p-value

Multivariate analysis OR [95% CI]

p-value

Age (yrs)

0.9 [0.9–1]

0.2

  

Gender Male (%)

1.5 [1.3–31]

0.06

  

Diabetes Mellitus (%)

0.8 [0.9–1.2]

0.2

  

Hypertension (%)

0.9 [0.8–1.1]

0.3

  

Coronary artery disease (%)

2.2 [1.01–4.8]

0.001

2.64 [1.04–6.7]

0.04

CKDa

1.7 [1.4–4.3]

0.03

  

NYHA class (%)

2 [1.2–3.5]

0.05

  

BNP (pg/ml)

1.0 [1–1.01]

0.04

  

Mitral regurgiation (%)

3 [1.3–6.5]

0.05

  

Rest E/e’

1.05 [0.9–1.2]

0.06

  

Rest ejection fraction (%)

1.13 [0.7–1.8]

0.59

  

Peak ejection fraction (%)

0.50 [0.3–0.8]

0.0059

  

Rest end-diastolic volume index (ml/m2)

1.0 [0.9–1.2]

0.97

  

Peak end-diastolic volume index (ml/m2)

1.17 [1.04–1.3]

0.07

  

Rest end-systolic volume index (ml/m2)

0.98 [0.8–1.2]

0.91

  

Peak end-systolic volume index (ml/m2)

1.81 [1.2–3.1]

0.05

  

Baseline LVMi (g/m2)

0.99 [0.97–1.01]

0.81

  

Baseline patterns of LV geometry

1.73 [1.3–2.9]

0.04

  

Peak cardiac power output-to-mass (Watt/100 g)

0.04 [0.02–0.19]

0.01

  

Peak LV elastance (mmHg/ml/m2)

8.3 [3.4–25]

< 0.0001

12.5 [4.5–33]

< 0.0001

  1. Legend: BNP, B-type natriuretic peptide; CKD, chronic kidney disease; E/e’, ratio of mitral E peak velocity and averaged e’ velocity; LV, left ventricular; LVMi, left ventricular mass indexed; NYHA, New York Heart Association
  2. aChronic kidney disease was defined as eGFR< 60 mL/min/1.73m2