Skip to main content

Table 6 Characteristics and genetic results in fetal TOF with extracardiac defects (TOF-Extra) group and in fetal TOF without extracardiac defects (TOF-no Extra) group

From: Genetic anomalies in fetuses with tetralogy of Fallot by using high-definition chromosomal microarray analysis

Characteristics

TOF-Extra (N = 49)

TOF-no Extra (N = 47)

P value

Maternal age, years

31 (19~42)

31 (21~38)

0.773

Gestational age at diagnosis, weeks

22+ 6 (16+ 2~30+ 1)

23+ 2 (18+ 5~31+ 4)

0.422

Intracardiac anomalies (%)

49.0 (24/49)

38.3 (18/47)

0.292

Genetic anomalies (%)

24.5 (12/49)

4.3 (2/47)

0.005

VOUS (%)

4.1 (2/49)

2.1 (1/47)

1.000

Cardiac angle (°)

50.4 (25.7~73.4)

50.2 (29.2~81.1)

0.613

Abnormal cardiac angle (%)

26.5 (13/49)

21.3 (10/47)

0.547

Survival rate (%)

87.5 (14/16)a

95.5 (21/22)a

0.562

  1. aCases that underwent selective reduction or termination of pregnancies were excluded. VOUS, variations of uncertain significance