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Table 6 Characteristics and genetic results in fetal TOF with extracardiac defects (TOF-Extra) group and in fetal TOF without extracardiac defects (TOF-no Extra) group

From: Genetic anomalies in fetuses with tetralogy of Fallot by using high-definition chromosomal microarray analysis

Characteristics TOF-Extra (N = 49) TOF-no Extra (N = 47) P value
Maternal age, years 31 (19~42) 31 (21~38) 0.773
Gestational age at diagnosis, weeks 22+ 6 (16+ 2~30+ 1) 23+ 2 (18+ 5~31+ 4) 0.422
Intracardiac anomalies (%) 49.0 (24/49) 38.3 (18/47) 0.292
Genetic anomalies (%) 24.5 (12/49) 4.3 (2/47) 0.005
VOUS (%) 4.1 (2/49) 2.1 (1/47) 1.000
Cardiac angle (°) 50.4 (25.7~73.4) 50.2 (29.2~81.1) 0.613
Abnormal cardiac angle (%) 26.5 (13/49) 21.3 (10/47) 0.547
Survival rate (%) 87.5 (14/16)a 95.5 (21/22)a 0.562
  1. aCases that underwent selective reduction or termination of pregnancies were excluded. VOUS, variations of uncertain significance