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Table 7 Prenatal ultrasound findings, genetic results and postnatal outcomes in fetal TOF with a normal cardiac angle group (TOF-CAn) and in fetal TOF with an abnormal cardiac angle group (TOF-CAab)

From: Genetic anomalies in fetuses with tetralogy of Fallot by using high-definition chromosomal microarray analysis

Characteristics TOF-CAn (N = 73) TOF-CAab (N = 23) P value
Maternal age, years 30 (20~42) 30 (19~38) 0.619
Gestational age at diagnosis, weeks 23+ 3 (16+ 2~30+ 3) 22+ 6 (18+ 5~31+ 4) 0.955
TOF type
 TOF-pulmonary valve atresia (%) 13.0 (11/73) 14.3 (3/23) 0.695
 TOF-pulmonary valve stenosis (%) 82.2 (60/73) 87.0 (20/23)
 TOF-an absent pulmonary valve syndrome (%) 2.7 (2/73) 0 (0/23)
Intracardiac anomalies (%) 43.8 (32/73) 39.1 (9/23) 0.691
Extracardiac defects (%) 50.7 (37/73) 52.2 (12/23) 0.901
Genetic anomalies (%) 6.8 (5/73) 39.1 (9/23) 0.001
VOUS (%) 1.4 (1/73) 8.7 (2/23) 0.142
Survival rate (%) 85.7 (18/19)a 88.9 (17/19)a 1.000
  1. aCases that underwent selective reduction or termination of pregnancies were excluded. VOUS, variations of uncertain significance
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Cardiovascular Ultrasound

ISSN: 1476-7120

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