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Table 3 Multivariable-adjusted associations of ejection work density with blood pressure components and arterial properties

From: Area of the pressure-strain loop during ejection as non-invasive index of left ventricular performance: a population study

 

Ejection work density (Pa)

 
 

All (n = 356)

Men (n = 197)

Women (n = 159)

 
 

Parameter estimate (95% CI)

P value

Parameter estimate (95% CI)

P value

Parameter estimate (95% CI)

P value

P int

Conventional (brachial) BP

 Systolic BP, + 16 mmHg

95.2 (76.8 to 113.6)

< 0.0001

82.8 (58.6 to 107.0)

< 0.0001

102.8 (74.7 to 130.9)

< 0.0001

0.074

 Diastolic BP, + 9.5 mmHg

37.2 (17.0 to 57.4)

0.0003

28.0 (3.93 to 52.1)

0.023

52.3 (18.3 to 86.3)

0.0028

0.096

 Pulse pressure, + 13 mmHg

82.1 (63.9 to 100.3)

< 0.0001

66.3 (43.2 to 89.4)

< 0.0001

94.2 (65.2 to 123.3)

< 0.0001

0.028

 MAP, +  10 mmHg

69.6 (50.8 to 88.4)

< 0.0001

57.4 (33.6 to 81.1)

< 0.0001

81.9 (52.4 to 111.5)

< 0.0001

0.043

SphygmoCor indexes

 AP, +  9 mmHg

59.1 (31.5 to 86.6)

< 0.0001

74.3 (33.2 to 115.2)

0.0005

50.0 (12.3 to 87.7)

0.0098

0.42

 Central PP, + 13 mmHg

65.7 (44.9 to 86.4)

< 0.0001

65.3 (37.4 to 93.2)

< 0.0001

62.5 (31.5 to 93.6)

0.0001

0.33

 PWV, 1.9 m/sa

44.8 (19.5 to 70.1)

0.0006

39.1 (7.87 to 70.3)

0.015

44.0 (1.82 to 86.2)

0.041

0.47

  1. The parameter estimates (95% confidence interval) indicate the change in EWD per 1 standard deviation increase in arterial index. All parameter estimates accounted for the variance explained by age, sex, heart rate and body height and weight. AP, central PP and PWV were additionally adjusted for MAP. Pint indicates the P values for an interaction between each arterial index and sex in predicting EWD. aData on arterial stiffness was available in 157 men and 117 women. AP indicates augmentation pressure, BP blood pressure, MAP mean arterial pressure, PP pulse pressure, PWV pulse wave velocity