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Table 4 Multivariable-adjusted associations between ejection work density and echocardiographic indexes of left atrial and left ventricular geometry

From: Area of the pressure-strain loop during ejection as non-invasive index of left ventricular performance: a population study

 

Ejection work density (Pa)

 
 

All (n = 356)

Men (n = 197)

Women (n = 159)

 

LV and LA geometry

Parameter estimate (95% CI)

P value

Parameter estimate (95% CI)

P value

Parameter estimate (95% CI)

P value

P int

LV dimensions

 Internal diameter, + 0.43 cm

10.7 (−14.2 to 35.6)

0.40

16.7 (−11.8 to 45.2)

0.25

10.0 (−34.9 to 55.0)

0.66

0.87

 Septal wall, + 0.14 cm

−7.99 (−32.8 to 16.9)

0.53

− 23.9 (−51.4 to 3.62)

0.088

23.4 (−22.6 to 69.5)

0.32

0.0063

 Posterior wall, + 0.12 cm

−14.8 (−40.2 to 10.6)

0.25

−34.3 (−61.1 to −7.42)

0.013

28.3 (− 22.5 to 79.1)

0.27

0.0014

 RWT, + 0.05

−13.2 (− 34.3 to 7.85)

0.22

−29.9 (−53.1 to − 6.66)

0.012

12.3 (− 27.0 to 51.6)

0.54

0.0069

 LV mass index, + 20 g/m2

6.06 (− 16.4 to 28.5)

0.60

−11.0 (−35.8 to 13.8)

0.38

46.1 (3.39 to 88.7)

0.035

0.0039

Volumes

 LA volume index, + 7.8 ml/m2

41.2 (19.2 to 63.2)

0.0003

23.9 (1.73 to 49.6)

0.067

76.2 (37.7 to 114.6)

0.0001

0.0019

 EDV index, + 10 ml/m2

23.0 (1.18 to 44.8)

0.039

12.3 (−13.1 to 37.7)

0.34

43.8 (5.30 to 82.3)

0.026

0.14

 ESV index, + 5 ml/m2

10.3 (−12.1 to 32.7)

0.37

−8.09 (−33.6 to 17.4)

0.53

39.8 (−0.90 to 80.5)

0.055

0.031

 Stroke volume, + 15 ml

27.9 (3.49 to 52.4)

0.025

25.6 (−1.69 to 52.8)

0.066

37.8 (−8.22 to 83.9)

0.11

0.73

 Ejection fraction, + 5.1%

11.5 (−7.26 to 30.2)

0.23

23.9 (1.16 to 46.6)

0.040

1.19 (−30.1 to 32.4)

0.94

0.13

  1. The parameter estimates (95% confidence interval) indicate the change in EWD per 1 standard deviation increase in the echocardiographic index. All parameter estimates accounted for the variance explained by age, sex, heart rate and body height and weight. Pint represents the P value for an interaction between each LV index and sex in predicting EWD. Adjustment for BSA-indexed measures did not include body height and weight. BSA indicates body surface area, EDV end-diastolic volume, ESV end-systolic volume, LA left atrial, PWT posterior wall thickness