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Table 1 Clinical Profile and General Doppler Echocardiographic Findings

From: Clinical value of myocardial performance index in patients with isolated diastolic dysfunction

  Control n = 51 DDI Patients n = 47 95% IC P
Age (yr) 38 ± 10 65 ± 10 23 to 31 < 0.001
Male/female 28/23 20/27 0.86 to 1.9 0.23
Body surface area (m2) 1.76 ± 0.18 1.68 ± 0.16 0.011 to 0.15 0.051
Hypertension 47 (100%)   
Diabetes 8 (17%)   
Smoking 5 (11%)   
Dyslipidemia 26 (55%)   
Heart rate (bpm) 66 ± 7.5 71 ± 8.6 2.62 to 8.9 < 0.001
SBP (mmHg) 113 ± 16 154 ± 22 33 to 48 < 0.001
DBP (mmHg) 67 ± 8.1 83 ± 13 10 to 19 < 0.001
Aortic root (mm) 31 ± 2.9 33 ± 3.6 1.3 to 4.0 < 0.001
Left atrium (mm) 30 ± 2.2 34 ± 4.0 2.7 to 5.3 < 0.001
LVDd (mm) 46 ± 2.9 47 ± 3.0 0.52 to 2.7 0.004
LVSd (mm) 29.4 ± 2.5 30 ± 2.8 −0.43 to 1.7 0.24
Septal thickness (mm)* 9.0 (7–10) 12.0 (12–14)   < 0.001
RWT (cm) 0.40 ± 0.03 0.52 ± 0.05 0.10 to 0.13 < 0.001
LV mass 141 ± 31 226 ± 46 70 to 101 < 0.0001
LV mass index (g/m2) 79 ± 12 134 ± 23 48 to 62 < 0.001
Fractional shortening (%) 36 ± 3.5 36.4 ± 4.3 −0.77 to 2.3 0.52
Ejection fraction (%) 65 ± 4.6 66 ± 5.4 −1.02 to 3.11 0.33
Medication
 ACE inhibitors/ARBs   28 (60%)   
 Diuretics   20 (43%)   
 Beta blockers   15 (32%)   
 Calcium-channel blockers   9 (19%)   
 Statins   17 (36%)   
  1. DDI, grade-I diastolic dysfunction patients; SBP, systolic blood pressure; DBP, diastolic blood pressure; LVDD, left ventricular diastolic diameter; LVSD, left ventricular systolic diameter; PWT, posterior-wall thickness; RWT, relative wall thickness; ACE, angiotensin-converting enzyme; ARB, angiotensin-receptor blocker
  2. Data expressed as mean ± standard deviation or median and 25-75th interquartile range
  3. * Mann-Whitney test