Table 1 Clinical Profile and General Doppler Echocardiographic Findings
From: Clinical value of myocardial performance index in patients with isolated diastolic dysfunction
Control n = 51 | DDI Patients n = 47 | 95% IC | P | |
|---|---|---|---|---|
Age (yr) | 38 ± 10 | 65 ± 10 | 23 to 31 | < 0.001 |
Male/female | 28/23 | 20/27 | 0.86 to 1.9 | 0.23 |
Body surface area (m2) | 1.76 ± 0.18 | 1.68 ± 0.16 | 0.011 to 0.15 | 0.051 |
Hypertension | – | 47 (100%) | ||
Diabetes | – | 8 (17%) | ||
Smoking | – | 5 (11%) | ||
Dyslipidemia | – | 26 (55%) | ||
Heart rate (bpm) | 66 ± 7.5 | 71 ± 8.6 | 2.62 to 8.9 | < 0.001 |
SBP (mmHg) | 113 ± 16 | 154 ± 22 | 33 to 48 | < 0.001 |
DBP (mmHg) | 67 ± 8.1 | 83 ± 13 | 10 to 19 | < 0.001 |
Aortic root (mm) | 31 ± 2.9 | 33 ± 3.6 | 1.3 to 4.0 | < 0.001 |
Left atrium (mm) | 30 ± 2.2 | 34 ± 4.0 | 2.7 to 5.3 | < 0.001 |
LVDd (mm) | 46 ± 2.9 | 47 ± 3.0 | 0.52 to 2.7 | 0.004 |
LVSd (mm) | 29.4 ± 2.5 | 30 ± 2.8 | −0.43 to 1.7 | 0.24 |
Septal thickness (mm)* | 9.0 (7–10) | 12.0 (12–14) | < 0.001 | |
RWT (cm) | 0.40 ± 0.03 | 0.52 ± 0.05 | 0.10 to 0.13 | < 0.001 |
LV mass | 141 ± 31 | 226 ± 46 | 70 to 101 | < 0.0001 |
LV mass index (g/m2) | 79 ± 12 | 134 ± 23 | 48 to 62 | < 0.001 |
Fractional shortening (%) | 36 ± 3.5 | 36.4 ± 4.3 | −0.77 to 2.3 | 0.52 |
Ejection fraction (%) | 65 ± 4.6 | 66 ± 5.4 | −1.02 to 3.11 | 0.33 |
Medication | ||||
ACE inhibitors/ARBs | 28 (60%) | |||
Diuretics | 20 (43%) | |||
Beta blockers | 15 (32%) | |||
Calcium-channel blockers | 9 (19%) | |||
Statins | 17 (36%) | |||