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Table 2 Univariate and multivariable analysis of correlation for anterior mitral leaflet lengths

From: Genetic relevance and determinants of mitral leaflet size in hypertrophic cardiomyopathy

 

Univariate analysis

Multivariable

Univariate analysis

Multivariable

AML-PLX (r)

AML-3CH (r)

AML-average (r)

AML-average (β, p value)

iAML-PLX (r)

iAML-3CH (r)

iAML-average (r)

iAML-average (β, p value)

Age

−0.123

− 0.221**

− 0.198**

 

0.145*

0.081

0.117

 

BSA

0.299**

0.281**

0.329**

0.292 (< 0.001)

    

LVEDV

0.246**

0.297**

0.315**

     

LVESV

0.257**

0.340**

0.341**

0.207 (0.002)

    

LVESWS

0.239**

0.323**

0.317**

     

LV ejection fraction

−0.118

−0.190**

−0.164*

     

LA volume

0.132

0.197**

0.174*

 

0.124

0.189**

0.180**

 

Maximal thickness

0.146*

0.225**

0.189**

     

LVOT-PPG (Resting)

0.039

0.044

0.033

 

0.244**

0.225**

0.230**

 

LVOT-PPG (Valsalva)

0.050

0.044

0.047

 

0.248**

0.240**

0.254**

0.110 (0.203)

MR grade

0.072

0.181**

0.147*

0.201 (0.004)

0.280**

0.390**

0.373**

0.146 (0.069)

E/e’

0.023

−0.049

−0.007

 

0.238**

0.188**

0.239**

 

LA wall stress

0.079

0.071

0.096

 

0.242**

0.243**

0.275**

0.212 (0.012)

CMR findings (n = 132)

 LV mass

0.301**

0.289**

0.338**

0.227 (0.013)†

    

 LVEDV

0.156

0.365**

0.291**

     

 LVESV

0,104

0.309**

0.228**

     
  1. *p < 0.05, **p < 0.01, †adjustment for BSA, MR grade, LVEDV and LVESV by CMR; BSA body surface area, LVESWS LV end-systolic wall stress. See abbreviations in Table 1