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Table 2 Univariate and multivariable analysis of correlation for anterior mitral leaflet lengths

From: Genetic relevance and determinants of mitral leaflet size in hypertrophic cardiomyopathy

  Univariate analysis Multivariable Univariate analysis Multivariable
AML-PLX (r) AML-3CH (r) AML-average (r) AML-average (β, p value) iAML-PLX (r) iAML-3CH (r) iAML-average (r) iAML-average (β, p value)
Age −0.123 − 0.221** − 0.198**   0.145* 0.081 0.117  
BSA 0.299** 0.281** 0.329** 0.292 (< 0.001)     
LVEDV 0.246** 0.297** 0.315**      
LVESV 0.257** 0.340** 0.341** 0.207 (0.002)     
LVESWS 0.239** 0.323** 0.317**      
LV ejection fraction −0.118 −0.190** −0.164*      
LA volume 0.132 0.197** 0.174*   0.124 0.189** 0.180**  
Maximal thickness 0.146* 0.225** 0.189**      
LVOT-PPG (Resting) 0.039 0.044 0.033   0.244** 0.225** 0.230**  
LVOT-PPG (Valsalva) 0.050 0.044 0.047   0.248** 0.240** 0.254** 0.110 (0.203)
MR grade 0.072 0.181** 0.147* 0.201 (0.004) 0.280** 0.390** 0.373** 0.146 (0.069)
E/e’ 0.023 −0.049 −0.007   0.238** 0.188** 0.239**  
LA wall stress 0.079 0.071 0.096   0.242** 0.243** 0.275** 0.212 (0.012)
CMR findings (n = 132)
 LV mass 0.301** 0.289** 0.338** 0.227 (0.013)†     
 LVEDV 0.156 0.365** 0.291**      
 LVESV 0,104 0.309** 0.228**      
  1. *p < 0.05, **p < 0.01, †adjustment for BSA, MR grade, LVEDV and LVESV by CMR; BSA body surface area, LVESWS LV end-systolic wall stress. See abbreviations in Table 1