Table 2 Baseline imaging characteristics
Overall (n = 80) | MCRSP + a (n = 33) | MCRSP – (n = 47) | p | |
|---|---|---|---|---|
Mitral Regurgitation | ||||
Regurgitant Severity | ||||
Regurgitant fraction (%) | 56 ± 16 | 53 ± 12 | 58 ± 19 | 0.19 |
EROA (cm2) | 0.6 ± 0.3 | 0.5 ± 0.3 | 0.6 ± 0.3 | 0.18 |
Regurgitant volume (ml) | 88 ± 39 | 80 ± 35 | 94 ± 41 | 0.13 |
Mitral Valve Morphology | ||||
Prolapse | 37% (30) | 39% (13) | 36% (17) | 0.77 |
Mitral annular calcification | 41% (33) | 45% (15) | 38% (18) | 0.52 |
Mitral valve thickening | 57% (46) | 55% (18) | 60% (28) | 0.65 |
Flail pathology | 14% (11) | 12% (4) | 15% (7) | 1.00 |
Left Ventricle | ||||
Ejection fraction (%) | 49 ± 15 | 48 ± 15 | 49 ± 15 | 0.99 |
Global Longitudinal Strain (%) | 15.8 ± 5.3 | 16.1 ± 4.8 | 15.3 ± 5.7 | 0.48 |
End-diastolic diameter (cm) | 6.0 ± 0.8 | 5.8 ± 0.7 | 6.2 ± 0.8 | 0.007 |
End-diastolic volume (ml/m2) | 104 ± 30 | 94 ± 25 | 111 ± 31 | 0.01 |
End-systolic diameter (cm) | 4.5 ± 1.1 | 4.3 ± 1.0 | 4.7 ± 1.1 | 0.10 |
End-systolic volume (ml/m2) | 56 ± 32 | 49 ± 27 | 61 ± 34 | 0.12 |
Mitral Annular Diameter | 3.36 ± 0.49 | 3.19 ± 0.45 | 3.48 ± 0.49 | 0.009 |
Myocardial mass (g/m2) | 112 ± 31 | 107 ± 28 | 116 ± 33 | 0.21 |
Relative wall thickness | 0.26 ± 0.05 | 0.28 ± 0.05 | 0.25 ± 0.05 | 0.02 |
Left Atrium | ||||
Diameter (cm) | 5.0 ± 1.1 | 4.8 ± 1.0 | 5.2 ± 1.1 | 0.10 |
2-Chamber area (cm2) | 32 ± 12 | 29.0 ± 7.6 | 34.5 ± 13.3 | 0.03 |
4-Chamber area (cm2) | 33 ± 10 | 28.6 ± 7.4 | 35.4 ± 10.8 | 0.003 |
Volume (ml/m2) | 73 ± 37 | 62 ± 27 | 82 ± 41 | 0.01 |
Global Circumferential Strain (%) | 13.4 ± 7.2 | 15.5 ± 7.6 | 12.0 ± 6.6 | 0.03 |
Global Longitudinal Strain (%) | 12.5 ± 5.1 | 14.1 ± 5.7 | 11.5 ± 4.3 | 0.02 |
Ejection Fraction (%) | 35 ± 15 | 37 ± 15 | 33 ± 16 | 0.19 |
Right Ventricle | ||||
TAPSE (cm) | 1.8 ± 0.6 | 1.8 ± 0.5 | 1.8 ± 0.6 | 0.55 |
S′ (cm/s) | 10.7 ± 3.0 | 10.3 ± 2.7 | 11.1 ± 3.2 | 0.23 |
Pulmonary artery systolic pressure (mmHg) | 52 ± 16 | 55 ± 18 | 51 ± 14 | 0.21 |