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Table 2 Characteristics of patients with CA and AS

From: Coexistence of aortic valve stenosis and cardiac amyloidosis: echocardiographic and clinical significance

Patient’s number, age (years) and sexType of CALV wall thickness (septum/posterior wall, mm) measured with echo, left ventricular ejection fraction (%), stroke volume index (ml/m2)Presence of typical LGE in CMR or semiquantitative score > 1 at PYP isotope scan in TTR amyloidCardiac biopsy positive for amyloidApical sparing at strain analysis.
(Average apical LS/(average
basal LS + mid-LS))
AVA/BSA (cm2/m2), and mean aortic valve gradient at rest, measured by TTE echoAVA/BSA (cm2/m2) and aortic valve gradient during dobutamine stress echoFinal diagnosis of the type of AS
1, 66, maleAL17/16, 48, 20yesDNPyes
0.45/BSA, 130.45/BSA, 22True-severe AS
2, 68, femaleAL13/13, 60, 40DNPDNPyes
0.65/14DNPModerate AS
3, 89, malewtTTR20/20, 51, 22yesDNPyes
0.54, 120.76, 19Pseudo-severe AS
4, 69, femaleAL20/15, 61, 31DNPyesyes
0.63, 22DNPModerate AS
5, 83, femaleAL12/12, 59, 38yesDNPyes
0.58, 190.86, 25Pseudo-severe AS
  1. AVA aortic valve area, LS longitudinal strain, TTE transthoracic echocardiography, NA not applicable, DNP did not performed. CA cardiac amyloidosis, AS aortic stenosis, PYP pyrophosphate, TTR transthyretin