Global peak left atrial longitudinal strain assessed by transthoracic echocardiography is a good predictor of left atrial appendage thrombus in patients in sinus rhythm with heart failure and very low ejection fraction – an observational study

Table 4 Results of the univariate regression models for prediction of secondary composite endpoint of death or hospitalization for ischemic stroke. Sorted by Gini coefficients

	OR	−95% CI OR	95% CI OR	p-value	Gini coefficient
CHA₂DS₂-VASc score	1.51	1.07	2.12	0.02	0.38
Age (years)	1.07	1.00	1.12	0.06	0.37
BSA (m²)	0.03	0.001	1.01	0.05	0.37
Chronic kidney disease	3.63	1.14	11.5	0.03	0.31
NYHA class					0.31
II	0.50	0.12	2.18	0.36
III	0.79	0.31	2.01	0.61
IV	2.52	0.98	6.47	0.05
Heart rate (bpm)	0.95	0.91	1.01	0.08	0.28
ACE-I or ARB	0.32	0.1	1.02	0.05	0.26
Diabetes	2.75	0.88	8.56	0.08	0.23
Ischaemic HF etiology	2.29	0.73	7.16	0.16	0.2
History of stroke or TIA	4.00	0.80	20.1	0.09	0.16
LA diameter (cm)	1.16	0.32	4.15	0.82	0.12
LAAT	1.57	0.50	4.93	0.44	0.1
Aspirin	2.00	0.39	10.3	0.41	0.09
LAVI (ml/ m²)	1.01	0.97	1.05	0.74	0.09
LVEF (%)	0.96	0.84	1.09	0.50	0.09
MRA	0.54	0.13	2.19	0.39	0.09
BMI (kg/m2)	1.00	0.89	1.13	0.94	0.08
E/e`	1.01	0.94	1.07	0.85	0.07
Global PACS (%)	1.13	0.71	1.79	0.62	0.07
E/A	1.11	0.68	1.84	0.67	0.06
Global PALS (%)	0.97	0.74	1.29	0.84	0.05
Beta-blocker	0.57	0.09	3.74	0.56	0.04
Digoxin	2.59	0.15	43.7	0.51	0.03
LA area (cm²)	0.99	0.92	1.07	0.83	0.03
Hypertension	1.09	0.37	3.28	0.87	0.02
Female sex	1.27	0.11	14.9	0.85	0.01
Other antiplatelet agent	0.93	0.22	3.97	0.92	0.01
Statin	0.95	0.31	2.93	0.93	0.01

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