Controls (n = 45) | CSFP (n = 60) | P-value | |
---|---|---|---|
Clinical characteristics | |||
Age (yrs) | 55.53 ± 8.44 | 56.52 ± 8.82 | 0.57 |
Male sex [n(%)] | 21 (47%) | 36 (60%) | 0.18 |
Systolic blood pressure (mm Hg) | 128.12 ± 14.44 | 125.94 ± 11.42 | 0.41 |
Diastolic blood pressure (mm Hg) | 76.71 ± 9.93 | 75.78 ± 9.91 | 0.63 |
Hypertension [n(%)] | 20 (44%) | 26 (43%) | 0.91 |
Diabetes mellitus [n(%)] | 2 (4%) | 5 (8%) | 0.70 |
Fasting blood glucose (mmol/L) | 5.41 ± 0.87 | 5.60 ± 0.97 | 0.29 |
Triglycerides (mmol/L) | 1.41 ± 0.83 | 1.43 ± 0.70 | 0.86 |
Total cholesterol (mmol/L) | 4.43 ± 0.80 | 4.35 ± 0.85 | 0.90 |
LDL cholesterol (mmol/L) | 2.67 ± 0.82 | 2.79 ± 0.75 | 0.45 |
HDL cholesterol (mmol/L) | 1.16 ± 0.30 | 1.07 ± 0.22 | 0.10 |
TFC | |||
cLAD | 21.77 ± 3.23 | 42.16 ± 16.11 | < 0.001 |
LCX | 21.47 ± 3.85 | 35.77 ± 16.53 | < 0.001 |
RCA | 21.20 ± 4.11 | 36.82 ± 18.76 | < 0.001 |
Mean | 21.48 ± 2.27 | 38.25 ± 13.57 | < 0.001 |
LV systolic function measurements | |||
LV end-diastolic volume (ml) | 82.27 ± 15.08 | 85.05 ± 16.92 | 0.38 |
LV ejection fraction (%) | 64.27 ± 4.44 | 63.03 ± 3.96 | 0.14 |
LV GLS (%) | −20.58 ± 2.36 | −19.24 ± 2.27 | 0.004 |
LV diastolic function measurements | |||
LA Volmax index | 27.76 ± 7.51 | 31.83 ± 8.47 | 0.03 |
Mitral E (m/s) | 74.89 ± 15.47 | 66.67 ± 17.24 | 0.01 |
Mitral E/A | 1.16 ± 0.37 | 0.96 ± 0.29 | 0.003 |
Mitral e’ (cm/s) | 8.67 ± 2.19 | 7.72 ± 1.69 | 0.01 |
Mitral E/e’ | 8.99 ± 2.26 | 8.86 ± 2.45 | 0.78 |
Tricuspid regurgitation velocity (m/s) | 2.01 ± 0.78 | 2.23 ± 0.89 | 0.56 |