From: In-vitro sonothrombolysis using thick-shelled polymer microbubbles - a comparison with thin-shelled microbubbles
Contrast agent
Shell material
Gas
Diameter and shell thickness
Resonance frequency
Thick-shelled MBs
(in-house made)
Polymer
Air
3.8 ± 0.6 μm
700 nm
12 MHz
Thin-shelled MBs
(SonoVue)
Phospholipid
Sulfur hexaflouride
2.5 (1–10 μm)
4 nm
1–4 MHz