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Table 4 Incremental Prognostic Effect of Echo Variables after Adjusting for Clinical Co-variablesa

From: Incremental prognostic value of echocardiography of left ventricular remodeling and diastolic function in STICH trial

 

Adjusted Effect of ECHO Variable

Adjusted Hazard Ratio (95% CI)

Models

Wald

Chi-Square

DF

P-value

LVESVI (> 65; Δ10 cc/m2)

44.3

1

< 0.001

1.12 (1.08, 1.15)

LVEF (≤ 30%; Δ1%)

31.9

1

< 0.001

0.95 (0.93, 0.97)

E/A ratio

29.1

2

< 0.001

 

 E/A ≤ 0.6 (Δ 0.1)

   

0.87 (0.72, 1.05)

 E/A 0.6–2.3 (Δ 0.1)

   

1.04 (1.03, 1.06)

MR severity (CFI grade 0, 1, 2, and 3–4)

25.9

1

< 0.001

1.31 (1.18, 1.45)

Deceleration time (≤190 ms, Δ10ms)

23.4

1

< 0.001

0.92 (0.90, 0.95)

E velocity (0.70–0.85; Δ1.0 m/s)

19.4

1

< 0.001

1.03 (1.02, 1.05)

E/e’ ratio (12–30; Δ1)

18.7

1

< 0.001

1.04 (1.02, 1.06)

LA volume index (Δ10 cc/m2)

16.2

1

< 0.001

1.14 (1.07, 1.22)

RV dysfunction (by quantitative grade)

16.2

1

< 0.001

1.26 (1.13, 1.41)

Sphericity index (0.66–0.88; Δ 0.1)

10.2

1

0.002

1.35 (1.12, 1.63)

  1. aClinical co-variables: surgical (CABG or CABG+SVR) vs medical treatment, age, creatinine, hemoglobin, history of stroke, history of atrial flutter/fibrillation, diabetes, and NYHA class
  2. EF Ejection fraction, LVESVI Left ventricular end systolic volume index, MR Mitral regurgitation, LA Left atrium, RV Right ventricle