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Table 2 Echocardiographic and cardiac catheterization data

From: Associations of 2D speckle tracking echocardiography-based right heart deformation parameters and invasively assessed hemodynamic measurements in patients with pulmonary hypertension

Parameter

All (n = 78)

PH (n = 45)

Non-PH (n = 33)

p-value

Echocardiographic data

 RA area, cm2

16.9 (13.0–24.9)

20.2 (15.8–27.0)

14.2 (12.3–18.0)

0.003

 RVED area, cm2

21.9 (17.9–25.6)

22.1 (18.7–27.3)

20.4 (15.8–25.4)

0.130

 RVES area, cm2

12.2 (9.9–15.6)

13.1 (10.8–17.1)

10.7 (9.3–13.4)

0.022

 FAC, %

41.3 (32.7–49.1)

41.0 (33.0–48.4)

43.5 (32.3–53.3)

0.749

 RV base diameter, mm

38.2 (33.5–42.9)

39.6 (34.6–43.9)

36 (30.3–40.7)

0.104

 RV mid diameter, mm

26.6 (22.1–32.7)

29.3 (22.4–34.6)

24.8 (21.5–31.5)

0.146

 RV apex-base diameter, mm

77.4 (66.3–84.2)

77.6 (66.3–84.9)

75.8 (66.4–81.8)

0.402

 RVOT mm

32.3 ± 4.3

32.5 ± 4.1

31.8 ± 4.5

0.54

 TAPSE, mm

19.8 ± 5.6

17.8 ± 5.4

22.3 ± 4.7

< 0.001

 RV-S′, cm/s

10.9 ± 3.1

10.0 ± 3.1

12.2 ± 2.6

0.003

 RVOT VTI

13.1. ± 4.0

12.0 ± 4.2

14.6 ± 3.2

0.006

 RV-e‘cm/s

10.7 ± 3.3

10.6 ± 3.8

10.7 ± 2.7

0.76

 RV-a’cm/s

12.7 ± 5.6

11.3 ± 6.4

14.2 ± 4.3

0.045

 LV ejection fraction, %

45.0 ± 13.4

39.0 ± 12.4

52.4 ± 11.0

< 0.001

   ≥ 55, n (%)

25 (32.1)

8 (17.8)

17 (51.5)

 

45–54, n (%)

17 (21.8)

8 (17.8)

9 (27.3)

 

30–44, n (%)

27 (34.6)

21 (46.7)

6 (18.2)

 

   ≤ 30, n (%)

9 (11.5)

8 (17.8)

1 (3.0)

 

 LV-GPLS

−13.6 ± 5.5

−11.2 ± 5.3

−16.5 ± 4.3

< 0.001

 Aortic valve regurgitation, n (%)

  

0.122

none

42 (53.8)

20 (44.4)

22 (66.7)

 

mild

25 (32.1)

16 (35.6)

9 (27.3)

 

moderate

9 (11.5)

8 (17.8)

1 (3)

 

  severe

2 (2.6)

1 (2.2)

1 (3)

 

 Aortic valve stenosis, n (%)

  

0.544

none

54 (69.2)

29 (64.4)

25 (75.8)

 

mild

1 (1.3)

1 (2.2)

0

 

moderate

1 (1.3)

1 (2.2)

0

 

severe

22 (28.2)

14 (31.1)

8 (24.2)

 

 Mitral valve regurgitation, n (%)

  

0.002

none

16 (20.5)

8 (17.8)

8 (24.2)

 

mild

27 (34.6)

9 (20.0)

18 (54.5)

 

moderate

30 (38.5)

25 (55.6)

5 (15.2)

 

severe

5 (6.4)

3 (6.7)

2 (6.1)

 

 Mitral valve stenosis, n (%)

  

0.675

none

75 (96.2)

43 (95.6)

32 (97.0)

 

mild

2 (2.6)

1 (2.2)

1 (3.0)

 

moderate

1 (1.3)

1 (2.2)

0

 

 Tricuspid valve regurgitation, n (%)

  

< 0.001

none

18 (23.1)

5 (11.1)

13 (39.4)

 

mild

31 (39.7)

16 (35.6)

15 (45.5)

 

moderate

21 (26.9)

16 (35.6)

5 (15.2)

 

severe

8 (10.3)

8 (17.8)

0

 

 Pulmonary valve regurgitation, n (%)

  

0.060

none

50 (64.1)

24 (53.3)

26 (78.8)

 

mild

27 (34.6)

20 (44.4)

7 (21.2)

 

severe

1 (1.3)

1 (2.2)

0

 

Catheterization data

 mPAP, mmHg

28.0 (21.0–36.0)

35.0 (30.0–42.5)

20.0 (17.0–22.5)

< 0.001

 PCWP, mmHg

20.0 ± 9.0

25.9 ± 6.8

11.8 ± 3.9

< 0.001

 Cardiac index, ml/min/m2

2.2 ± 0.6

2.0 ± 0.6

2.4 ± 0.4

0.001

 LVEDP, mmHg

20.0 (14.5–27.5)

24.5 (21.0–30.7)

15.0 (13.0–17.5)

< 0.001

 SVR, dyn x sec x cm−5

1619.5 (1345–2029.0)

1712.0 (1344–2178.0)

1536.0 (1334–1794.0)

0.189

 PVR, dyn x sec x cm−5

205.5 (138.2–251.0)

212.0 (164.5–288.5)

180.0 (111.0–238.5)

0.056

  1. Data are expressed as mean ± SD, median with IQR, or absolute numbers and respective percentages. PH, pulmonary hypertension; RA, right atrial; RV, right ventricular; RVED and RVES, RV end diastolic and end systolic; FAC, fractional area change; TAPSE, tricuspid annular plane systolic excursion; RV-S′, RV peak systolic velocity; LV-GLPS, left ventricular global longitudinal peak systolic strain; LVEDP, left ventricular enddiastolic pressure; mPAP, mean pulmonary artery pressure; PCWP, pulmonary capillary wedge pressure; SVR, systemic vascular resistance; PVR, pulmonary vascular resistance