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Table 2 Echocardiographic and cardiac catheterization data

From: Associations of 2D speckle tracking echocardiography-based right heart deformation parameters and invasively assessed hemodynamic measurements in patients with pulmonary hypertension

ParameterAll (n = 78)PH (n = 45)Non-PH (n = 33)p-value
Echocardiographic data
 RA area, cm216.9 (13.0–24.9)20.2 (15.8–27.0)14.2 (12.3–18.0)0.003
 RVED area, cm221.9 (17.9–25.6)22.1 (18.7–27.3)20.4 (15.8–25.4)0.130
 RVES area, cm212.2 (9.9–15.6)13.1 (10.8–17.1)10.7 (9.3–13.4)0.022
 FAC, %41.3 (32.7–49.1)41.0 (33.0–48.4)43.5 (32.3–53.3)0.749
 RV base diameter, mm38.2 (33.5–42.9)39.6 (34.6–43.9)36 (30.3–40.7)0.104
 RV mid diameter, mm26.6 (22.1–32.7)29.3 (22.4–34.6)24.8 (21.5–31.5)0.146
 RV apex-base diameter, mm77.4 (66.3–84.2)77.6 (66.3–84.9)75.8 (66.4–81.8)0.402
 RVOT mm32.3 ± 4.332.5 ± 4.131.8 ± 4.50.54
 TAPSE, mm19.8 ± 5.617.8 ± 5.422.3 ± 4.7< 0.001
 RV-S′, cm/s10.9 ± 3.110.0 ± 3.112.2 ± 2.60.003
 RVOT VTI13.1. ± 4.012.0 ± 4.214.6 ± 3.20.006
 RV-e‘cm/s10.7 ± 3.310.6 ± 3.810.7 ± 2.70.76
 RV-a’cm/s12.7 ± 5.611.3 ± 6.414.2 ± 4.30.045
 LV ejection fraction, %45.0 ± 13.439.0 ± 12.452.4 ± 11.0< 0.001
   ≥ 55, n (%)25 (32.1)8 (17.8)17 (51.5) 
45–54, n (%)17 (21.8)8 (17.8)9 (27.3) 
30–44, n (%)27 (34.6)21 (46.7)6 (18.2) 
   ≤ 30, n (%)9 (11.5)8 (17.8)1 (3.0) 
 LV-GPLS−13.6 ± 5.5−11.2 ± 5.3−16.5 ± 4.3< 0.001
 Aortic valve regurgitation, n (%)  0.122
none42 (53.8)20 (44.4)22 (66.7) 
mild25 (32.1)16 (35.6)9 (27.3) 
moderate9 (11.5)8 (17.8)1 (3) 
  severe2 (2.6)1 (2.2)1 (3) 
 Aortic valve stenosis, n (%)  0.544
none54 (69.2)29 (64.4)25 (75.8) 
mild1 (1.3)1 (2.2)0 
moderate1 (1.3)1 (2.2)0 
severe22 (28.2)14 (31.1)8 (24.2) 
 Mitral valve regurgitation, n (%)  0.002
none16 (20.5)8 (17.8)8 (24.2) 
mild27 (34.6)9 (20.0)18 (54.5) 
moderate30 (38.5)25 (55.6)5 (15.2) 
severe5 (6.4)3 (6.7)2 (6.1) 
 Mitral valve stenosis, n (%)  0.675
none75 (96.2)43 (95.6)32 (97.0) 
mild2 (2.6)1 (2.2)1 (3.0) 
moderate1 (1.3)1 (2.2)0 
 Tricuspid valve regurgitation, n (%)  < 0.001
none18 (23.1)5 (11.1)13 (39.4) 
mild31 (39.7)16 (35.6)15 (45.5) 
moderate21 (26.9)16 (35.6)5 (15.2) 
severe8 (10.3)8 (17.8)0 
 Pulmonary valve regurgitation, n (%)  0.060
none50 (64.1)24 (53.3)26 (78.8) 
mild27 (34.6)20 (44.4)7 (21.2) 
severe1 (1.3)1 (2.2)0 
Catheterization data
 mPAP, mmHg28.0 (21.0–36.0)35.0 (30.0–42.5)20.0 (17.0–22.5)< 0.001
 PCWP, mmHg20.0 ± 9.025.9 ± 6.811.8 ± 3.9< 0.001
 Cardiac index, ml/min/m22.2 ± 0.62.0 ± 0.62.4 ± 0.40.001
 LVEDP, mmHg20.0 (14.5–27.5)24.5 (21.0–30.7)15.0 (13.0–17.5)< 0.001
 SVR, dyn x sec x cm−51619.5 (1345–2029.0)1712.0 (1344–2178.0)1536.0 (1334–1794.0)0.189
 PVR, dyn x sec x cm−5205.5 (138.2–251.0)212.0 (164.5–288.5)180.0 (111.0–238.5)0.056
  1. Data are expressed as mean ± SD, median with IQR, or absolute numbers and respective percentages. PH, pulmonary hypertension; RA, right atrial; RV, right ventricular; RVED and RVES, RV end diastolic and end systolic; FAC, fractional area change; TAPSE, tricuspid annular plane systolic excursion; RV-S′, RV peak systolic velocity; LV-GLPS, left ventricular global longitudinal peak systolic strain; LVEDP, left ventricular enddiastolic pressure; mPAP, mean pulmonary artery pressure; PCWP, pulmonary capillary wedge pressure; SVR, systemic vascular resistance; PVR, pulmonary vascular resistance