|Author Year (Ref #)||
Type of disease|
|Baccouche 2012 ||CA (n = 12) / HCM (n = 12)||To differentiate two pathologies.||
1) Basal LS, CS and RS were significantly reduced in patients with CA compared with HCM.|
2) Regional strain values were irreversibly correlated with LGE, and the best correlation was observed between RS and LGE (r = −0.82)
|Aly 2014 ||HCM mutation carriers (n = 23) / HCM (n = 28) / control (n = 29)||To detect early changes in myocardial mechanics in HCM mutations.||
1) There were no significant differences in 3D global/regional strains between HCM mutations and control subjects.|
2) 3D global/regional LS and AS were significantly impaired in HCM compared with HCM mutations.
3) 3D GCS and 3DGRS were not different between HCM and HCM mutations.
|Tadic 2015 ||HT with normal LV geometry (n = 85) / concentric LV remodeling (n = 28) / eccentric nondilated LVH (42) / concentric LVH (n = 30) / dilated and concentric-dilated LVH (n = 12)||To investigate LV mechanics in HT with different geometric patterns||
1) 2D and 3D global strains decreased normal geometry, followed by concentric remodeling, eccentric nondilated LVH, concentric LVH, dilated LVH and concentric dilated LVH.|
2) Reduced 2D and 3D strains were associated with concentric and dilated LVH patterns independent of demographic and clinical parameters.
|Urbano-Moral 2015 ||AL amyloidosis (n = 40)||To detect cardiac involvement.||
1) 3D GLS and GCS were significantly lower in patients with cardiac involvement than those without.|
2) Prominent reduction of LS/CS was observed in the basal myocardium.
|Voilliot 2015 ||HCM (n = 40) / control (n = 53)||To assess impact of hypertrophy on strains.||
Compared to control subjects,|
1) 3D GLS, GAS, and GRS were significantly lower in HCM patients.
2) No significant differences in 3D GCS were noted.
3) 3D regional LS/AS was significantly depressed irrespective to the degree of hypertrophy.
4) 3D regional CS was higher in no or mildly hypertrophied segments.
|Ternacle 2017 ||Athlete with moderate LVH (n = 25) / Athlete without LVH (n = 25) / HCM (n = 25) / control (n = 25)||To differentiate patients with HCM from athletes with moderate LVH.||
1) 2D GLS and 3D GLS were significantly lower in HCM than athletes with moderate LVH.|
2) 2D LV dyssynchrony index (SD of time to peak LS in 16 segment model) had a highest AUC for identifying HCM in the presence of moderate LVH.
3) 3D GCS was not different between the two groups.
|Cho 2017 ||Severe AS with normal LVEF (≥ 55%, n = 45) / control (n = 18)||To evaluate early myocardial dysfunction||
1) 2D GLS and 3D GLS were significantly impaired in severe AS patients with increased LV wall thickness compared with normal LV wall thickness.|
2) 3D GCS, GAS, and GRS did not show any differences between the two groups.
|Pradel 2019 ||AL amyloidosis (n = 58) / control (n = 21)||To detect LV dysfunction.||
1) There were no significant differences in 3D LVEF and 3D global strains between Mayo Clinic Stage I AL amyloidosis and control subjects.|
2) 3D LVEF and 3D global strains decreased according to the advanced Mayo Clinic stage.