Local myocardial stiffness variations identified by high frame rate shear wave echocardiography

Table 3 2D longitudinal strain analysis in the study group

*Parameter*	*Group 1* Normal volunteers	*Group 2* HCM patients without septal reduction	ANOVA p 1 vs 2	*Group 3* HCM patients post septal reduction	ANOVA p 1 vs 3	ANOVA p 2 vs 3
GLS (%)	-20 ± 2	−19 ± 4	0.9	−14 ± 5	0.001	0.004
Average septal^a LSS 4 chambers (%)	−23 ± 3	−16 ± 4	< 0.0001	−13 ± 4	< 0.0001	0.2
Average septal^a LSS 3 chambers (%)	−20 ± 4	−16 ± 4	0.04	−10 ± 4	< 0.0001	0.01
Any^a septal LSS > − 10% (number)	0	0	–	10 subjects	–	–
Any^a septal LSS > −5% (number)	0	0	–	3 subjects	–	–

^a: the septal basal and mid-wall segments were considered, in the 4 chambers and 3 chambers views. GLS Global Longitudinal Strain; LSS Longitudinal segmental strain

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