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Table 2 Baseline Echocardiographic data and Speckle Tracking Echocardiographic parameters

From: Comparison of global and regional myocardial strains in patients with heart failure with a preserved ejection fraction vs hypertension vs age-matched control

 

HFpEF (n = 50)

HTN (n = 56)

Age-matched control (n = 46)

P value

Mean ± SD or n (%)

Echocardiographic parameter

 LVEDD (mm)

48.2 ± 5.04

48.6 ± 4.21

47.6 ± 3.39

0.456

 LVESD (mm)

28.8 ± 3.98

28.4 ± 3.52

28.5 ± 2.72

0.889

 IVSd (mm)

10.2 ± 2.71

9.11 ± 1.58

8.22 ± 1.28

<  0.001*

 LVPWd (mm)

9.97 ± 2.14

8.62 ± 1.49

8.04 ± 1.38

<  0.001*

 LV MI (g/m2, mean ± SEM)

90.7 ± 29.6

83.8 ± 20.2

75.6 ± 19.4

0.011*

 Relative wall thickness

0.42 ± 0.11

0.36 ± 0.07

0.34 ± 0.06

<  0.001*

 LVH by ASE guideline

12 (24.0)

8 (14.3)

2 (4.3)

0.010 *

 LVEDV (ml)

101.0 ± 31.9

106.9 ± 25.9

107.9 ± 19.5

0.408

 LVESV (ml)

35.7 ± 13.2

39.0 ± 11.7

38.9 ± 12.9

0.328

 LAVI by area-length method (ml/m2)

38.9 ± 13.7

32.6 ± 7.89

30.9 ± 6.73

<  0.001*

 LVEF (%)

64.9 ± 5.85

63.8 ± 5.11

64.0 ± 4.23

0.554

 Stroke volume (ml)

85.3 ± 26.3

77.4 ± 16.5

72.9 ± 14.2

0.009 *

 Cardiac output (L/min)

5.57 ± 1.7

5.28 ± 1.2

5.13 ± 1.2

0.298

 Cardiac index (L/min/m2)

2.86 ± 0.7

2.95 ± 0.6

3.07 ± 0.8

0.344

 E (m/sec)

0.83 ± 0.23

0.60 ± 0.16

0.62 ± 0.16

<  0.001*

 A (m/sec)

0.75 ± 0.28

0.73 ± 0.16

0.67 ± 0.17

0.214

 Septal e’(m/sec)

0.064 ± 0.021

0.063 ± 0.015

0.075 ± 0.018

0.002*

 E/e’

14.30 ± 6.37

9.82 ± 2.93

8.51 ± 2.57

<  0.001*

 Deceleration time

231.1 ± 54.9

240.8 ± 41.5

234.13 ± 44.5

0.572

Speckle Tracking Echocardiographic parameter

 Global longitudinal strain value

  Strain, %

−15.52 ± 5.32

−17.75 ± 3.12

−19.88 ± 2.04

<  0.001*

  Strain rate, 1/s

0.97 ± 0.35

1.35 ± 0.29

1.60 ± 0.25

<  0.001*

 Global circumferential strain value

  Strain, %

- 9.27 ± 2.19

−19.30 ± 3.14

−20.53 ± 3.30

<  0.001*

  Strain rate, 1/s

1.03 ± 0.25

1.75 ± 0.42

1.94 ± 0.46

<  0.001*

 Global radial strain value

  Strain, %

17.67 ± 8.22

38.39 ± 12.43

43.63 ± 11.92

<  0.001*

  Strain rate, 1/s

−1.24 ± 0.48

− 1.85 ± 0.51

− 1.89 ± 0.39

<  0.001*

  1. The p-value denotes statistical significance comparing HFpEF, HTN and age-matched controls. *P <  0.05 by ANOVA (analysis of variance) or χ2-test. Data are listed as numbers (percentage of group), mean value. ASE, American society of echocardiography; EDD, end-diastole dimension; EDV, end-diastolic volume; EF, ejection fraction; ESD, end-systolic dimension; ESV, end-systolic volume; HFpEF, heart failure with preserved ejection fraction; HTN, hypertension; IVSd, interventricular septum thickness at end-diastole; LAVI, Left atrial volume index; LV, left ventricular; LVH, LV hypertrophy; PWd, posterior wall thickness at end-diastole; SD, standard deviation.; SEM, standard error of the mean
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Cardiovascular Ultrasound

ISSN: 1476-7120

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