| |
Diastolic dysfunction grade 1
|
Diastolic dysfunction grade 2 or 3
|
p-value
|
|---|
|
(n = 30)
|
(n = 20)
|
|---|
|
Age, years
|
62 ± 15
|
68 ± 14
|
0.15
|
|
Females, n (%)
|
11 (37)
|
8 (40)
|
0.81
|
|
Hypertension, n (%)
|
19 (63)
|
19 (95)
|
0.01
|
|
Diabetes Mellitus, n (%)
|
12 (40)
|
14 (70)
|
0.04
|
|
Ischemic Cardiomyopathy, n (%)
|
20 (67)
|
11 (55)
|
0.41
|
|
Chronic Kidney Diseasea, n (%)
|
5 (17)
|
5 (25)
|
0.47
|
|
Heart rate, beats/min
|
73 [63, 75]
|
74 [62, 85]
|
0.33
|
|
LVEF, %
|
40 [35, 45]
|
35 [29, 41]
|
0.04
|
|
LAVI, ml/m2
|
25.2 ± 5.9
|
39.3 ± 5.9
|
< 0.001
|
|
LVMI, g/m2
|
114 ± 30
|
137 ± 40
|
0.03
|
|
LVEDD, mm
|
53 [46, 58]
|
57 [52, 60]
|
0.06
|
|
E, cm/s
|
65 [54, 74]
|
106 [95, 128]
|
< 0.001
|
|
A, cm/s
|
77 [63, 89]
|
63 [43, 3]
|
0.07
|
|
E/A ratio
|
0.88 [0.66, 1.05]
|
2.00 [1.50, 2.80]
|
< 0.001
|
|
DT, ms
|
206 ± 49
|
161 ± 50
|
0.003
|
|
e’ lateral, cm/s
|
7.3 ± 2.5
|
6.4 ± 2.0
|
0.16
|
|
E/e’ lateral ratio
|
9.8 [7.0, 11.8]
|
18.1 [14.0, 19.5]
|
< 0.001
|
- Data are presented as mean ± SD or median [interquartile range]. LVEF left ventricular ejection fraction, LAVI left atrial volume index, LVMI left ventricular mass index, LVEDD left ventricular end-diastolic diameter, DT deceleration time. adenotes at least moderate chronic kidney disease (CKD) stage (3A or higher) as defined by the National Kidney Foundation
