Left atrial functional assessment and mortality in patients with severe aortic stenosis with sinus rhythm

Table 4 Discriminative power of echocardiographic parameters for all-cause mortality

Variables	AUC	95% CI	*P-value*	*Sensitivity (%)*	*Specificity (%)*	*Criterion*
LAEF (%)	0.845	0.807–0.879	< 0.001	56	92	37
LAAEF (%)	0.812	0.768–0.850	< 0.001	71	82	23
LATEVi (mL)	0.783	0.738–0.824	< 0.001	60	84	17
E/e’ ratio	0.772	0.721–0.817	< 0.001	63	79	20
Septal e’ velocity (cm/s)	0.758	0.706–0.804	< 0.001	71	67	4
LAAEVi (mL)	0.723	0.672–0.770	< 0.001	57	80	7
LAPEF (%)	0.709	0.660–0.755	< 0.001	42	89	17
AVA (cm²)	0.661	0.612–0.709	< 0.001	67	57	0.7
RV/RA gradient (mmHg)	0.627	0.556–0.693	0.001	42	77	32
LAPEVi (mL)	0.626	0.572–0.678	< 0.001	49	71	9
LAVi (mL)	0.625	0.574–0.674	< 0.001	67	56	44
LVEF (%)	0.613	0.564–0.660	< 0.001	42	79	56
TAPSE (mm)	0.573	0.523–0.621	0.010	64	47	21
Aortic MPG (mmHg)	0.555	0.505–0.604	0.058	16	96	34
V_max (m/s)	0.550	0.500–0.599	0.085	38	72	4.2

AUC denotes area under the curve, AVA aortic valve area, LAAEF left atrial active emptying fraction, LAAEVi indexed left atrial active emptying volume, LAEF left atrial emptying fraction, LAPEF left atrial passive emptying fraction, LAPEVi indexed left atrial passive emptying volume, LATEVi indexed left atrial total emptying volume, LAVi indexed left atrial maximum volume, LVEF left ventricular ejection fraction, MPG mean pressure gradient, TAPSE tricuspid annular plane systolic excursion, RV/RA right ventricle/right atrium.

ISSN: 1476-7120