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Table 1 Clinical and echocardiographic characteristics of the study population

From: Comparison of left atrial and left atrial appendage mechanics in the risk stratification of stroke in patients with atrial fibrillation

 

Overall (N = 208)

Stroke/TIA (N = 31)

Control (N = 177)

P value

Clinical characteristics

 Gender,male

133 (63.9)

20 (64.5)

113 (63.8)

0.94

 Age,years

63.58 ± 10.37

68.32 ± 7.57

62.75 ± 10.59

< 0.01

 Body mass index,kg/m2

24.37 ± 3.20

24.72 ± 3.07

24.31 ± 3.22

0.52

 Heart failure

33 (15.9)

10 (32.3)

23 (13.0)

< 0.01

 Coronary artery disease

37 (17.8)

7 (22.6)

30 (16.9)

0.45

 Hypertension

111 (53.4)

19 (61.3)

92 (52.0)

0.34

 Diabetes

45 (21.6)

8 (25.8)

37 (20.9)

0.54

 Hyperlipoproteinemia

58 (27.9)

5 (16.1)

53 (29.9)

0.11

 Persistent AF

120 (57.7)

20 (64.5)

100 (56.5)

0.40

 Anticoagulation

145 (69.7)

23 (74.2)

122 (68.9)

0.56

 CHA2DS2-VASc score before stroke

1.82 ± 1.26

2.29 ± 1.16

1.73 ± 1.26

0.02

Conventional echocardiographic parameters

 iLVESV,mL/m2

24.18 ± 9.40

27.82 ± 14.40

23.56 ± 8.17

0.13

 iLVEDV,mL/m2

66.84 ± 14.55

70.56 ± 17.95

66.21 ± 13.85

0.13

 LVEF,%

64.26 ± 8.24

61.58 ± 8.73

64.72 ± 8.09

0.05

 iLAAPd,mm/ m2

22.77 ± 3.82

23.48 ± 3.72

22.64 ± 3.83

0.26

 iLAVmin,mL/m2

27.88 ± 15.48

34.86 ± 18.81

26.63 ± 14.53

< 0.01

 iLAVmax,,mL/m2

41.67 ± 17.08

47.79 ± 22.96

40.57 ± 15.63

0.03

 LAEF, %

35.2 ± 16.00

28.56 ± 13.69

36.39 ± 16.13

0.01

 LAAEV,m/s

0.53 ± 0.24

0.45 ± 0.25

0.54 ± 0.23

0.09

 LAAFV,m/s

0.53 ± 0.20

0.47 ± 0.23

0.54 ± 0.20

0.10

 LAA dense SEC/thrombus

36 (18.5)

11 (40.7)

25 (14.9)

< 0.01

 ilAAVmin,mL/m2

1.89 ± 1.58

2.06 ± 1.53

1.86 ± 1.59

0.53

 iLAAVmax,mL/m2

4.24 ± 2.41

4.12 ± 2.58

4.26 ± 2.38

0.77

 LAAEF,%

57.30 ± 19.83

51.86 ± 16.81

58.19 ± 20.19

0.13

Strain echocardiographic parameters

 LA GLS,%

18.08 ± 9.64

13.09 ± 7.01

19.99 ± 9.79

< 0.01

 LA MD,%

8.91 ± 3.76

11.56 ± 4.38

8.43 ± 3.44

< 0.01

 LAA GLS,%

12.15 ± 5.82

9.01 ± 3.12

12.66 ± 6.00

< 0.01

 LAA MD,%

11.53 ± 4.78

15.15 ± 5.46

10.94 ± 4.40

< 0.01

  1. Data are expressed as mean ± SD or N (%)
  2. AF atrial fibrillation, EDV end-diastolic volume, ESV end-systolic volume, GLS global longitudinal strain, i indexed to body surface area, LA left atrium, LAA left atrial appendage, LAA EF LAA emptying fraction, LAAEV LAA emptying velocity, LAAFV LAA filling velocity, LAAPd LA anteroposterior diameter, LAEF LA emptying fraction, LV left ventricle, LVEF left ventricular ejection fraction, MD mechanical dispersion, SEC spontaneous echo contrast, TIA transient ischaemic attack, Vmax maximal volume, Vmin minimal volume