Table 2 Univariable and multivariable logistic regression analyses of associations between clinical and echocardiographic covariates with stroke
Variables | Univariate analysis | Multivariate analysis | ||||||
|---|---|---|---|---|---|---|---|---|
OR (95% CI) | P value | Model 1 | Model 2 | Model 3 | ||||
OR (95% CI) | P value | OR (95% CI) | P value | OR (95% CI) | P value | |||
Clinical parameters | ||||||||
 Age | 1.07 (1.02–1.12) | < 0.01 | 1.06 (1.01–1.13) | 0.03 | 1.07 (1.01–1.14) | 0.03 | 1.08 (1.01–1.40) | 0.02 |
 Female | 1.03 (0.46–2.29) | 0.94 | 2.17 (0.79–6.02) | 0.14 | 2.44 (0.85–7.03) | 0.09 |  |  |
 Heart failure | 3.19 (1.33–7.62) | 0.01 | 1.85 (0.63–5.45) | 0.27 | 1.56 (0.48–5.24) | 0.46 |  |  |
 CHA2DS2-VASc score | 1.41 (1.04–1.19) | 0.03 | 1.04 (0.55–1.97) | 0.91 | 1.14 (0.57–2.29) | 0.71 | 1.07 (0.57–1.63) | 0.71 |
LA parameters | ||||||||
 LAEF | 0.97 (0.94–0.99) | 0.01 | 1.00 (0.96–1.04) | 0.99 |  |  |  |  |
 iLAVmax | 1.02 (1.00–1.04) | 0.03 | 0.99 (0.96–1.02) | 0.53 |  |  | 0.99 (0.96–1.03) | 0.81 |
 LA GLS | 0.91 (0.86–0.97) | < 0.01 | 0.99 (0.90–1.09) | 0.88 | 0.99 (0.89–1.10) | 0.77 | 0.99 (0.89–1.09) | 0.78 |
 LA MD | 1.25 (1.22–1.39) | < 0.01 | 1.20 (1.07–1.36) | < 0.01 | 1.29 (1.11–1.49) | < 0.01 | 1.18 (1.03–1.34) | < 0.01 |
LAA parameters | ||||||||
 LAAEV | 0.18 (0.02–1.33) | 0.09 |  |  | 16.81 (1.28–220.9) | 0.03 | 4.83 (0.45–52.15) | 0.05 |
 LAAEF | 0.98 (0.97–1.00) | 0.13 |  |  | 1.01 (0.98–1.05) | 0.45 |  |  |
 LAA dense SEC/thrombus | 3.93 (1.64–9.46) | < 0.01 |  |  | 4.39 (1.33–14.53) | 0.02 | 3.63 (1.16–11.35) | 0.03 |
 LAA GLS | 0.84 (0.75–0.94) | < 0.01 | 0.96 (0.85–1.09) | 0.53 | 0.96 (0.84–1.10) | 0.57 | 0.96 (0.84–1.09) | 0.49 |
 LAA MD | 1.21 (1.09–1.32) | < 0.01 | 1.19 (1.07–1.33) | < 0.01 | 1.22 (1.08–1.38) | < 0.01 | 1.21 (1.08–1.36) | < 0.01 |