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Table 2 Univariate and multivariate analysis for a’ velocity

From: Contribution of sarcomere gene mutations to left atrial function in patients with hypertrophic cardiomyopathy

  a’ LA dysfunction (a’ < 6 cm/s)
Univariate analysis Multivariate analysis Univariate analysis Multivariate analysis
(r) (p) (β) (p) OR (95% CI) p OR (95% CI) p
Age, per year 0.102 0.166    0.98 (0.95–1.01) 0.098   
Dynamic obstruction −0.069 0.348    3.68 (1.60–8.45) 0.002   
ApHCM 0.182 0.013 0.057 0.341 0.38 (0.16–0.90) 0.029 1.34 (0.39–4.57) 0.638
LVEF-by echo, per % 0.030 0.683    0.93 (0.88–0.99) 0.015   
E, per cm/s −0.260 < 0.001    26.39 (3.40–204.94) 0.002   
A, per cm/s 0.291 < 0.001    0.06 (0.006–0.49) 0.009   
e’, per 100 cm/s 0.232 0.001    0.74 (0.57–0.97) 0.030   
E/e’ 0.411 < 0.001 −0.089 0.190 1.17 (1.08–1.25) < 0.001 1.07 (0.97–1.17) 0.182
s’, per 100 cm/s 0.592 < 0.001 0.484 < 0.001 0.47 (0.34–0.65) < 0.001 0.52 (0.34–0.78) 0.001
LA volume index, per mL/m2 −0.418 < 0.001 − 0.200 0.002 1.05 (1.03–1.07) < 0.001 1.04 (1.01–1.07) 0.004
Presence of sarcomere mutations 0.211 0.004 −0.138 0.017 4.76 (2.05–11.02) < 0.001 5.33 (1.71–16.61) 0.004
LV mass index by CMR (n = 135) −0.214 0.021    1.02 (1.00–1.05) 0.046   
Presence of LGE (n = 133) −0.248 0.007    1.89 (0.49–7.21) 0.353   
No of LGE segment (n = 133) −0.334 < 0.001    1.26 (1.07–1.49) 0.006   
%LGE mass (n = 133) −0.132 0.156    1.03 (0.97–1.09) 0.312   
LV myocardial GLS (n = 135) −0.045 0.627    1.05 (0.93–1.18) 0.435   
LA GLS (n = 135), per % 0.076 0.413    0.92 (0.85–0.99) 0.034   
LA minimal volume (n = 135), per mL −0.443 < 0.001    1.03 (1.02–1.05) < 0.001   
LA maximal volume (n = 135), per mL −0.427 < 0.001    1.02 (1.01–1.04) 0.001   
LA total emptying fraction (n = 135), per % 0.251 0.006    0.93 (0.89–0.97) 0.001   
LA active emptying fraction (n = 119), per % 0.248 0.006    0.93 (0.88–0.97) 0.003   
5-yr-SCD risk (n = 123) −0.314 0.001    1.45 (1.06–1.99) 0.020   
Presence of NSVT (n = 123) −0.214 0.036    5.27 (1.58–17.66) 0.007   
  1. Abbreviations are same as in Table 1