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Table 3 Univariate and multivariate analysis for left atrial total emptying fraction

From: Contribution of sarcomere gene mutations to left atrial function in patients with hypertrophic cardiomyopathy

LA total emptying fraction (%) by CMR Univariate analysis Multivariate analysis
(r) (p) (β) (p)
Age, per year −0.334 < 0.001 −0.265 < 0.001
Dynamic obstruction 0.163 0.069   
ApHCM 0.148 0.089   
E/e’ −0.178 0.038 − 0.052 0.497
s’, per cm/s 0.370 < 0.001 0.164 0.043
a’, per cm/sa 0.251 0.006   
Presence of sarcomere mutations −0.226 0.008 − 0.171 0.015
LV mass index by CMR, g/m2 −0.040 0.647   
Presence of LGE (n = 133) −0.086 0.218   
No of LGE segment (n = 133) −0.172 0.048   
%LGE mass (n = 133) −0.182 0.036 0.042 0.566
LVEF by CMR, per % 0.274 0.001 0.103 0.186
LV myocardial GLS, per % −0.537 < 0.001 −0.429 < 0.001
LA GLS, per %a 0.824 < 0.001   
LA minimal volume, per mLa −0.677 < 0.001   
LA maximal volume, per mLa −0.408 < 0.001   
LA active emptying fraction (n = 119), per %a 0.879 < 0.001   
  1. aDue to collinearity to LA total emptying fraction, they were not included in the multivariate analysis. See abbreviations in Table 1