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Table 2 Preoperative and follow-up values for left ventricular and left atrial dimensions, volumes, and function

From: Pre- and postoperative left atrial and ventricular volumetric and deformation analyses in severe aortic regurgitation

 

Aortic regurgitation (n = 65)

Controls (n = 20)

Baseline comparison

Baseline

Follow-up

p value

Baseline

Follow-up

p value

p value

Left ventricular indices

 End-diastolic diameter (mm)

62.6 ± 6

49.3 ± 6

< 0.001

48.5 ± 3

46.2 ± 4

0.005

< 0.001

 End-systolic diameter (mm)

44.0 ± 7

34.4 ± 5

< 0.001

33.1 ± 4

32.5 ± 4

0.80

< 0.001

 Interventricular septum (mm)

11.7 ± 2.0

12.2 ± 1.7

0.004

11.3 ± 2.0

11.4 ± 1.7

0.71

0.48

 Posterior wall thickness (mm)

10.3 ± 1.4

9.5 ± 1.8

0.003

8.9 ± 1.7

9.3 ± 1.6

0.29

< 0.001

 End-diastolic volume (mL)

224 ± 62

132.4 ± 36

< 0.001

109 ± 20

111 ± 23

0.25

< 0.001

 End-diastolic volume index (mL/m2)

113 ± 30

66 ± 17

< 0.001

56 ± 9

57 ± 10

0.40

< 0.001

 End-systolic volume (mL)

103 ± 41

57 ± 18

< 0.001

43 ± 8

45 ± 11

0.25

< 0.001

 End-systolic volume index (mL/m2)

52 ± 20

28 ± 8

< 0.001

22 ± 4

23 ± 5

0.41

< 0.001

 Stroke volume (mL)

121 ± 31

76 ± 22

< 0.001

65 ± 14

66 ± 15

0.41

< 0.001

 Ejection fraction (%)

55 ± 7.3

57 ± 7.1

0.027a

60 ± 4

60 ± 7

0.79

< 0.001

 Global longitudinal strain (|%|)

19.0 ± 3.0

19.4 ± 2.5

0.34

19.9 ± 2

19.6 ± 2

0.54

0.24

 Left ventricular mass index (g/m2)

81 ± 19

62 ± 16

< 0.001

48 ± 11

48 ± 11

0.87

< 0.001

Diastolic function indices

 Mitral E velocity (m/s)

0.76 ± 0.2

0.73 ± 0.2

0.17

0.70 ± 0.2

0.76 ± 0.2

0.14

0.23

 Mitral A velocity (m/s)

0.58 ± 0.2

0.59 ± 0.2

0.84

0.63 ± 0.2

0.66 ± 0.2

0.38

0.30

 Mitral E/A ratio

1.5 ± 0.7

1.3 ± 0.5

0.063

1.3 ± 0.8

1.2 ± 0.6

0.93

0.17

 Mitral E-wave Deceleration time (ms)

205 ± 57

238 ± 52

0.001

212 ± 44

232 ± 52

0.11

0.66

 Septal e′ (m/s)

0.074 ± 0.02

0.075 ± 0.02

0.85

0.066 ± 0.02

0.070 ± 0.02

0.46

0.11

 Lateral e′ (m/s)

0.097 ± 0.03

0.12 ± 0.03

0.005

0.087 ± 0.02

0.10 ± 0.01

0.071

0.13

 Mitral average E/e′ ratio

9.3 ± 3

8.0 ± 3

0.012

10.2 ± 3

9.1 ± 2

0.31

0.30

 Tricuspid regurgitation velocity (m/s)

2.5 ± 0.3

2.3 ± 0.4

0.080

2.3 ± 0.2

2.3 ± 0.2

0.33

0.047a

Diastolic dysfunction grade

 0 or 1

39 (60%)

55 (85%)

0.003

20 (100%)

18 (90%)

0.30

0.002

 2

6 (9%)

2 (3%)

 

0

1 (5%)

  

 3

15 (23%)

5 (8%)

 

0

0

  

 Indeterminate

5 (8%)

3 (4%)

 

0

1 (5%)

  

Left atrial indices

 Left atrial volume index (ml/m2)

38.6 ± 12

32.2 ± 11

< 0.001

26.8 ± 8

27.4 ± 8

0.70

< 0.001

 LASr (%)

26.3 ± 6.7

29.0 ± 6.2

0.012

25.7 ± 6.0

25.8 ± 4.7

0.92

0.86

 LAScd (%)

15.6 ± 6.1

14.0 ± 4.5

0.037a

12.1 ± 3.5

11.9 ± 3.7

0.28

0.081

 LASct (%)

11.0 ± 4.7

15.3 ± 5.5

< 0.001

12.8 ± 5.6

13.8 ± 4.2

0.43

0.049a

  1. aNon-significant after Bonferroni correction at α = 0.017; e′, tissue doppler-derived mitral annular early diastolic velocity, LAScd Left atrial strain conduit phase, LASct Left atrial strain contraction phase, LASr Left atrial strain reservoir phase
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Cardiovascular Ultrasound

ISSN: 1476-7120

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