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Table 3 Left atrial strain and NTproBNP levels in patients with aortic regurgitation (based on diastolic dysfunction grade) and controls

From: Pre- and postoperative left atrial and ventricular volumetric and deformation analyses in severe aortic regurgitation

  Aortic regurgitation (n = 60) Controls (n = 20) Overall p value
DD grades 0 or 1 (n = 39) DD grades 2 or 3 (n = 21)
LASr (%) 27.9 ± 5.1* 23.8 ± 7.8 25.7 ± 6.0 0.030
LAScd (%) 15.3 ± 6.8 15.8 ± 6.8 12.1 ± 3.5 0.26
LASct (%) 12.6 ± 4.2* 8.0 ± 3.7 12.8 ± 5.6 < 0.001
LASct/LASr ratio 0.47 ± 0.15* 0.34 ± 0.13 0.50 ± 0.14 0.001
NTproBNP (NPX units) 3.79 ± 1.61* 5.03 ± 1.54 3.53 ± 1.31 0.002
  1. DD Diastolic dysfunction, LAScd Left atrial conduit phase, LASct Left atrial contraction phase, LASr Left atrial reservoir phase, NPX units Normalized protein expression units (log2 scale), NTproBNP N-terminal pro-B-type natriuretic peptide. *p < 0.05 for the comparison between DD grades 0 or 1 and DD grades 2 or 3, p < 0.05 for the comparison between DD grades 2 or 3 and the control group