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Table 1 Baseline characteristics of the study population, stratified by outcome

From: Left ventricular global longitudinal strain predicts elevated cardiac pressures and poor clinical outcomes in patients with non-ischemic dilated cardiomyopathy

Variables

Total

Event-free group (n = 21)

Adverse cardiac event group (n = 20)

p-value

Clinical characteristics

  Age, years

47.0 ± 11.64

48.8 ± 10.0

45.2 ± 13.2

0.32

  Male gender, n (%)

33 (80)

18 (86)

15 (75)

0.42

  NYHA III-IV class, n (%)

36 (88)

17 (81)

19 (95)

0.34

  Systolic BP, mm Hg

114 (104, 130)

120 (110, 130)

110 (103, 120)

0.09

  Diastolic BP, mm Hg

80 (70, 80)

80 (70, 80)

73 (69, 80)

0.21

Concomitant cardiac medication/

  ACE-I/ARB, n (%)

31 (76)

17 (81)

14 (70)

0.48

  Beta-blocker, n (%)

39 (95)

20 (95)

19 (95)

1

  MRA, n (%)

37 (90)

19 (95)

18 (86)

0.6

  Loop diuretics, n (%)

38 (93)

19 (91)

19 (95)

1

Biomarkers

  eGFR, ml/min/1.73 m2

83 (71, 102)

83 (73, 100)

86 (71, 103)

0.82

  BNP, ng/l

809 (79, 1523)

300 (47, 851)

1294 (506. 2920)

 < 0.01

  Troponin T, pg/ml

29.1 (17.3, 46.5)

23.6 (9.4, 41.7)

33 (25.2, 65.2)

0.09

Hemodynamic measurements

  mPAP, mmHg

28 (21, 38)

23 (21, 34)

33 (27, 40)

0.09

  Elevated mPAP (> 20 mmHg), n (%)

33 (80)

17 (81)

16 (80)

1

  PCWP, mmHg

19 (15, 27)

17 (14, 22)

22 (16, 33)

0.18

  Elevated PCWP (> 15 mmHg), n (%)

27 (66)

12 (57)

15 (75)

0.23

  PVR, Wood units

1.9 (1.2, 3.1)

1.6 (1, 2.4)

2.5 (1.8, 3.5)

 < 0.05

  Elevated PVR (≥ 3 Wood units), n (%)

10 (25)

3 (15)

7 (35)

0.14

  Cardiac index, l/min/m2

2.3 ± 0.7

2.4 ± 0.6

2.2 ± 0.8

0.49

  1. Values are expressed as: mean ± SD, median (25th percentile, 75th percentile) or n (%)
  2. ACE-I Angiotensin-converting enzyme inhibitor, ARB Angiotensin II receptor blocker, BNP B type natriuretic peptide, BP Blood pressure, eGFR Estimated glomerular filtration rate, mPAP mean pulmonary arterial pressure, MRA Mineralocorticoid receptor antagonist, NYHA New York Heart Association, PCWP pulmonary capillary wedge pressure, PVR pulmonary vascular resistance