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Table 4 ROC analysis for identifying elevated hemodynamic parameters by echocardiographic markers

From: Left ventricular global longitudinal strain predicts elevated cardiac pressures and poor clinical outcomes in patients with non-ischemic dilated cardiomyopathy

 

AUC (95% CI)

PAWP ≥ 15 mmHg

mPAP > 20 mmHg

PVR > 3 Wood units

DT, ms

0.61 (0.42–0.79)

0.60 (0.37–0.81)

0.68 (0.49–0.86)

E/A

0.68 (0.49–0.86)

0.69 (0.45–0.90)

0.85 (0.68–0.98)

Average E/e’

0.62 (0.41–0.80)

0.53 (0.29–0.76)

0.67 (0.46–0.85)

TR velocity, m/s

0.68 (0.49–0.85)

0.66 (0.42–0.90)

0.51 (0.23–0.78)

LAVi, ml/m2

0.68 (0.50–0.85)

0.78 (0.60–0.95)

0.76 (0.57–0.92)

LVEF, %

0.65 (0.43–0.83)

0.63 (0.41–0.85)

0.66 (0.47–0.84)

GLS, %

0.74 (0.57–0.88)

0.65 (0.45–0.86)

0.78 (0.60–0.95)

E/GLS, [× 102] cm/s

0.76 (0.59–0.91)

0.72 (0.49–0.92)

0.84 (0.68–0.96)

  1. The bold font character means statistically significance (p < 0.05)
  2. AUC area under the curve, 95% CI 95% confidence interval, DT deceleration time, E/A ratio of early-diastolic LV inflow velocity (E) to atrial-systolic velocity (A), E/e’ ratio of early-diastolic LV inflow velocity (E) to early-diastolic mitral annular velocity (e´), E/GLS ratio of early-diastolic LV inflow velocity (E) to global longitudinal strain (GLS), GLS global longitudinal strain, LAVi left atrium indexed volume, PCWP pulmonary capillary wedge pressure, mPAP mean pulmonary arterial pressure, PVR pulmonary vascular resistance, TR tricuspid regurgitation