Left ventricular global longitudinal strain predicts elevated cardiac pressures and poor clinical outcomes in patients with non-ischemic dilated cardiomyopathy

Table 5 Results of Cox regression analysis for predictors of adverse cardiac events during short-term follow-up

	Univariate		Multivariate
	HR (95% CI)	p	HR (95% CI)	p
Systolic BP, mm Hg	0.95 (0.9–0.99)	0.03
Diastolic BP, mm Hg	0.93 (0.86–0.998)	0.04
BNP, ng/l	1.001 (1–1.001)	< 0.0001	1.001 (1.0–1.0014)	< 0.01
Troponin T, pg/ml	1.004 (1–1.008)	0.03	1.007 (1.002–1.01)	< 0.01
mPAP, mmHg	1.09 (1.03–1.16)	< 0.01
PCWP, mmHg	1.16 (1.06–1.28)	< 0.01
PVR, Wood units	1.53 (1.13–2.08)	< 0.01
Cardiac index, l/min/m²	0.16 (0.04–0.77)	0.02
Severely impaired RV systolic function	5.29 (1.32–21.14)	0.02
RV end-diastolic diameter, cm	2.44 (1.08–5.52)	0.03
LVEF, %	0.8 (0.69–0.92)	< 0.01	0.84 (0.72–0.99)	0.04
LV GLS, %	1.55 (1.19–2.03)	< 0.001
E/GLS [× 10²], cm/s	0.96 (0.93–0.995)	0.02

BNP B type natriuretic peptide, BP Blood pressure, CI confidence interval, E/GLS ratio of early-diastolic LV inflow velocity (E) to global longitudinal strain (GLS), GLS global longitudinal strain, HR hazard ratio, LVEF left ventricular ejection fraction, mPAP mean pulmonary arterial pressure, PCWP pulmonary capillary wedge pressure, PVR pulmonary vascular resistance, RV right ventricle

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