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Table 3 Adjusted comparison of fetal cardiac indices between groups and subgroups

From: Evaluation of prenatal changes in fetal cardiac morphology and function in maternal diabetes mellitus using a novel fetal speckle-tracking analysis: a prospective cohort study

Indices

Difference between GDM and controls at 24+0–27+6 weeks

Difference between GDM and controls at 28+0–40+0 weeks

Difference in controls between 24+0–27+6 weeks and 28+0–40+0 weeks

Difference in GDM between 24+0–27+6 weeks and 28+0–40+0 weeks

Coefficient (95% CI)

P-value

Coefficient (95% CI)

P-value

Coefficient (95% CI)

P-value

Coefficient (95% CI)

P-value

4CV-GSI

-0.30 (-0.53, 0)

0.022

-0.44 (-0.65, -0.14)

0.001

-0.02 (-0.27, 0.30)

0.865

-0.24 (-0.51, 0.04)

0..085

LV-GLS

0.87 (0.81, 0.91)

0.000

0.77 (0.64, 0.86)

0.000

0.08 (-0.18, 0.35)

0.579

0.01 (-0.30, 0.36)

0.961

RV-GLS

0.86 (0.79, 0.91)

0.000

0.73 (0.59, 0.83)

0.000

-0.03 (-0.32, 0.30)

0.807

-0.07 (-0.33, 0.21)

0.637

LV-FAC

-0.58 (-0.73, -0.41)

0.000

-0.54 (-0.71, -0.29)

0.000

-0.11 (-0.40, 0.22)

0.434

-0.03 (-0.29, 0.22)

0.855

RV-FAC

-0.57 (-0.75, -0.36)

0.000

-0.63 (-0.80, -0.39)

0.000

0.08 (-0.22, 0.41)

0.555

0.08 (-0.20, 0.38)

0.573

  1. Adjustment made for maternal age, BMI and EFW
  2. GDM gestational diabetes mellitus, 4CV four-chamber view, GSI global sphericity index, LV left ventricle, GLS global longitudinal strain, RV right ventricle, FAC fractional area change