Table 5 Diagnostic accuracy by visual and strain imaging for detecting significant coronary stenoses
Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) | Accuracy (%) | Optimal cut-off | AUC (95% CI) | p-value | |
|---|---|---|---|---|---|---|---|---|
Visual assessment | ||||||||
Overall examination | 94.3 | 73.1 | 64.7 | 96.1 | 80.4 | N/A | 0.84 (0.73 – 0.94) | Ref. |
LAD | 65.5 | 80.8 | 57.6 | 85.5 | 76.5 | N/A | 0.73 (0.66 – 0.80) | Ref. |
Non-LAD | 53.3 | 87.5 | 64.0 | 81.8 | 77.5 | N/A | 0.70 (0.66 – 0.75) | Ref. |
Stress GLS | ||||||||
Overall examination | 68.6 | 68.7 | 53.3 | 80.7 | 68.7 | -19.9 | 0.69 (0.58 – 0.80) | 0.006 |
LAD | 72.4 | 69.9 | 48.8 | 86.4 | 70.6 | -21.2 | 0.75 (0.64 – 0.86) | 0.63 |
Non-LAD | 56.7 | 65.3 | 40.5 | 78.3 | 62.8 | -15.0 | 0.60 (0.47 – 0.72) | 0.09 |
Delta GLS | ||||||||
Overall examination | 42.9 | 92.5 | 75.0 | 75.6 | 75.5 | 4.1 | 0.69 (0.57 – 0.80) | 0.01 |
LAD | 72.4 | 76.7 | 55.3 | 87.5 | 75.5 | 1.1 | 0.75 (0.63 – 0.87) | 0.67 |
Non-LAD | 43.3 | 80.6 | 48.2 | 77.3 | 69.6 | 3.7 | 0.60 (0.47 – 0.72) | 0.10 |
Stress apical segment STE | ||||||||
Overall examination (S13-17) | 51.4 | 89.6 | 72.0 | 77.9 | 76.5 | -21.2 | 0.76 (0.65 – 0.86) | 0.15 |
LAD (segment 17) | 62.1 | 86.3 | 64.3 | 85.1 | 79.4 | -21.8 | 0.78 (0.67 – 0.89) | 0.23 |
Non-LAD (S15 and 16) | 66.7 | 77.8 | 55.6 | 84.9 | 74.5 | -22.8 | 0.77 (0.67 – 0.87) | 0.38 |
Delta apical segment STE | ||||||||
Overall examination (S13-17) | 65.7 | 82.1 | 65.7 | 82.1 | 76.5 | 2.1 | 0.76 (0.65 – 0.86) | 0.16 |
LAD (segment 17) | 72.4 | 76.7 | 55.3 | 87.5 | 75.5 | 1.8 | 0.78 (0.66 – 0.89) | 0.31 |
Non-LAD (S15 and 16) | 66.7 | 77.8 | 55.6 | 84.9 | 74.5 | 1.9 | 0.76 (0.65 – 0.86) | 0.49 |
Visual assessment with delta apical segment strain STE if visual assessment positivea | ||||||||
Overall examination | 94.3 | 77.6 | 68.8 | 96.3 | 83.3 | 4.8 | 0.89 (0.82 – 0.96) | 0.025 |
LAD | 69.0 | 87.7 | 69.0 | 87.7 | 82.4 | 4.8 | 0.79 (0.67 – 0.90) | 0.11 |
Non-LAD | 73.3 | 87.5 | 71.0 | 88.7 | 83.3 | -2.8 | 0.83 (0.73 – 0.92) | 0.006 |