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Table 2 Distribution of diastolic measurements in patients with severe aortic stenosis

From: Echocardiographic assessment of diastolic dysfunction in elderly patients with severe aortic stenosis before and after aortic valve replacement

   n Range; percent within range (%) Mean ± SD P (Chi Square)
  Range (cm/s)   < 5 5–7 7–10 ≥10    
e’septal (cm/s) Before SAVR/TAVR 128 65% 24% 9% 2%   5.1 ± 3.9 0.166
After SAVR/TAVR 132 53% 36% 10% 1%   5.2 ± 1.6  
e’lateral (cm/s) Before SAVR/TAVR 128 31% 35% 29% 5%   6.3 ± 2.1 < 0.0001
After SAVR/TAVR 132 12% 34% 38% 16%   7.7 ± 2.7  
e’avrg (cm/s) Before SAVR/TAVR 128 44% 36% 18% 2%   5.7 ± 2.4 < 0.0001
After SAVR/TAVR 132 21% 45% 33% 2%   6.5 ± 1.8  
  Range (cm/s)   < 8 8–12 12–16 16–20 ≥20   
E/e’sept () Before SAVR/TAVR 125 3% 7% 18% 22% 50% 22 ± 11 0.222
After SAVR/TAVR 130 3% 14% 24% 20% 39% 20 ± 10  
E/e’lat () Before SAVR/TAVR 128 7% 26% 25% 17% 25% 16 ± 8 0.051
After SAVR/TAVR 132 13% 36% 24% 12% 14% 14 ± 7  
E/e’avrg () Before SAVR/TAVR 127 5% 12% 28% 26% 30% 19 ± 8 0.014
After SAVR/TAVR 132 5% 28% 27% 23% 18% 16 ± 7  
  Range (ms)   < 60 60–80 80–100 100–120 > 120   
IVRT Before SAVR/TAVR 128 40% 26% 17% 9% 7% 70 ± 44 0.007
After SAVR/TAVR 123 24% 22% 21% 20% 13% 90 ± 54  
  Range (mmHg)   < 30 30–40 40–50 ≥50    
PAP Before SAVR/TAVR 122 17% 47% 22% 14%   39 ± 8 0.046
After SAVR/TAVR 130 22% 55% 19% 5%   36 ± 8  
  Range (%)   < 25 25–40 50–60 50–80    
PV SFF Before SAVR/TAVR 133 5% 17% 40% 38%   51 ± 17 0.048
After SAVR/TAVR 133 9% 17% 50% 23%   49 ± 14  
  Range (ml/m2)   < 34 34–50 50–75 > 75    
LA volume Index Before SAVR/TAVR 123 16% 33% 45% 7%   52 ± 20 0.093
After SAVR/TAVR 129 16% 46% 33% 7%   50 ± 23  
  Range (cm/s)   < 50 50–80 80–110 > 110    
MV peak E Before SAVR/TAVR 130 4% 28% 27% 42%   96 ± 32 0.415
After SAVR/TAVR 132 3% 36% 21% 40%   95 ± 32  
MV peak A Before SAVR/TAVR 102 10% 13% 26% 52%   102 ± 32 0.299
After SAVR/TAVR 102 2% 22% 21% 56%   105 ± 28  
  Range ()   < 0.5 0.5–0.8 0.8–1.1 ≥1.1    
MV E/A () Before SAVR/TAVR 101 13% 43% 27% 18%   1.0 ± 0.6 0.009
After SAVR/TAVR 101 10% 41% 40% 11%   1.0 ± 0.4  
  Range (ms)   < 150 150–220 220–280 > 280    
E decel time Before SAVR/TAVR 130 13% 30% 19% 39%   251 ± 95 0.050
After SAVR/TAVR 132 5% 28% 30% 37%   260 ± 76  
  Range (ng/L)   < 500 500–850 850–1700 1700–5000 > 5000   
NT-proBNP Before SAVR/TAVR 119 23% 16% 19% 30% 13% 3168 ± 6270 < 0.0001
After SAVR/TAVR 120 43% 19% 21% 13% 4% 1274 ± 2238  
  Range ()   0 (Normal) 1 (Normal) 2 (inde-terminate) 3 (positive) 4 (positive)   
Score 2016 Before SAVR/TAVR 117 3% 9% 22% 40% 26% 2.7 ± 1.0 0.071
After SAVR/TAVR 128 2% 13% 35% 36% 15% 2.5 ± 1.0  
  Range ()   0 (Normal) 1 2 3    
2009 Criteria for Grade I, II or III Before SAVR/TAVR 127 1% 8% 20% 72%   2.6 ± 1 < 0.0001
After SAVR/TAVR 130 2% 20% 28% 51%   2.3 ± 1  
  1. 2009 Criteria for Grade I, II or III diastolic dysfunction were septal e′ < 8, lateral e′ < 10, LA ≥34 ml/m2, displayed is the number of criteria met
  2. A Late (atrial) diastolic transmitral flow velocity, E Early diastolic transmitral flow velocity, e′ Early diastolic mitral annuler velocity, IVRT Isovolumic relaxation time, LA Left atrium, MV dec time Mirtal valve deceleration time, MV peak E Mitral valve early diastolic filling velocity, MV peak A Mitral valve late diastolic atrial filling velocity, NT-proBNP N-terminal prohormone of brain natriuretic peptide, PAP Pulmonary artery pressure, PV SFF Pulmonary veins systolic filling fraction, SAVR Surgical aortic valve replacement, TAVR Transcatheter aortic valve replacement