Echocardiographic assessment of diastolic dysfunction in elderly patients with severe aortic stenosis before and after aortic valve replacement

Table 4 Univariate and multivariate regression analysis for indicators of elevated NT-proBNP (≥500 ng/L)

	Univariate regression (Unadjusted model)				Multivariate regression (Adjusted model)
	OR	95% CI	95%C I	p-value	OR	95% CI	95% CI	p-value
e’septal (cm/s)	0.731	0.632	0.845	< 0.0001	1.196	1.118	1.279	< 0.0001*
e’lateral (cm/s)	0.921	0.847	1.002	0.056
e’avrg (cm/s)	0.807	0.713	0.913	0.001
E/e’sept ()	1.108	1.071	1.147	< 0.0001	1.196	1.118	1.1279	< 0.0001*
E/e’lat ()	1.079	1.039	1.127	< 0.0001
E/e’avrg ()	1.090	1.040	1.142	< 0.0001
PV SFF	0.947	0.929	0.965	< 0.0001
LA volume (ml)	1.022	1.013	1.030	< 0.0001
MV peak E (cm/s)	1.019	1.010	1.027	< 0.0001	0.965	0.949	0.982	0.001
MV peak A (cm/s)	0.999	0.991	1.007	0.782
MV E/A ()	2.278	1.210	4.289	0.011
MV dec time (ms)	0.994	0.991	0.997	< 0.0001	0.994	0.991	0.998	0.001
IVRT (ms)	0.997	0.993	1.001	0.192
PAP (mmHg)	1.114	1.097	1.192	< 0.0001	1.095	1.039	1.154	0.001

*E’sept or E/é avrg exclude each other in the equation and can be used interchangeably
A Late (atrial) diastolic transmitral flow velocity, E Early diastolic transmitral flow velocity, e′ Early diastolic mitral annuler velocity, IVRT Isovolumic relaxation time, LA Left atrium, MV dec time Mirtal valve deceleration time, MV peak E Mitral valve early diastolic filling velocity, MV peak A Mitral valve late diastolic atrial filling velocity, NT-proBNP N-terminal prohormone of brain natriuretic peptide, PAP Pulmonary artery pressure, PV SFF Pulmonary veins systolic filling fraction

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