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Table 4 Univariate and multivariate regression analysis for indicators of elevated NT-proBNP (≥500 ng/L)

From: Echocardiographic assessment of diastolic dysfunction in elderly patients with severe aortic stenosis before and after aortic valve replacement

  Univariate regression (Unadjusted model) Multivariate regression (Adjusted model)
OR 95% CI 95%C I p-value OR 95% CI 95% CI p-value
e’septal (cm/s) 0.731 0.632 0.845 < 0.0001 1.196 1.118 1.279 < 0.0001*
e’lateral (cm/s) 0.921 0.847 1.002 0.056     
e’avrg (cm/s) 0.807 0.713 0.913 0.001     
E/e’sept () 1.108 1.071 1.147 < 0.0001 1.196 1.118 1.1279 < 0.0001*
E/e’lat () 1.079 1.039 1.127 < 0.0001     
E/e’avrg () 1.090 1.040 1.142 < 0.0001     
PV SFF 0.947 0.929 0.965 < 0.0001     
LA volume (ml) 1.022 1.013 1.030 < 0.0001     
MV peak E (cm/s) 1.019 1.010 1.027 < 0.0001 0.965 0.949 0.982 0.001
MV peak A (cm/s) 0.999 0.991 1.007 0.782     
MV E/A () 2.278 1.210 4.289 0.011     
MV dec time (ms) 0.994 0.991 0.997 < 0.0001 0.994 0.991 0.998 0.001
IVRT (ms) 0.997 0.993 1.001 0.192     
PAP (mmHg) 1.114 1.097 1.192 < 0.0001 1.095 1.039 1.154 0.001
  1. *E’sept or E/é avrg exclude each other in the equation and can be used interchangeably
  2. A Late (atrial) diastolic transmitral flow velocity, E Early diastolic transmitral flow velocity, e′ Early diastolic mitral annuler velocity, IVRT Isovolumic relaxation time, LA Left atrium, MV dec time Mirtal valve deceleration time, MV peak E Mitral valve early diastolic filling velocity, MV peak A Mitral valve late diastolic atrial filling velocity, NT-proBNP N-terminal prohormone of brain natriuretic peptide, PAP Pulmonary artery pressure, PV SFF Pulmonary veins systolic filling fraction