Echocardiographic assessment of diastolic dysfunction in elderly patients with severe aortic stenosis before and after aortic valve replacement

Table 5 Cut-off values, sensitivity and specificity for detection of elevated NT-proBNP

	N pos	N neg	A			B			C
	N pos	N neg	Cut-off A	Sensitivity (%)	Specificity (%)	Cut-off B	Sensitivity (%)	Specificity (%)	Cut off C	Sensitivity (%)	Specificity (%)
e’septal (cm/s)	227	129	6.0	83	35	5.5	75	53	5.0	64	60
e’avrg (cm/s)	227	129	7.0	72	39	6.0	65	56	5.5	45	72
E/e’sept ()	227	129	16	72	50	18	64	65	20	55	76
E/e’avrg ()	227	129	14	67	57	15	58	66	16	54	70
PV SFF	220	128	60	80	41	55	67	63	50	55	77
LA volume (ml)	227	130	70	85	43	80	73	60	90	61	75
PAP (mmHg)	220	128	30	84	31	35	61	74	40	41	90
Peak E (cm/s)	228	130	80	68	45	90	59	63	100	52	81
E DT (ms)	228	130	280	68	52	250	59	68	220	44	81
Score of the parameters above			<Cut-off A: -1			Cut-off A to C = 0			>Cut-off C: +1
Sum Score of e’septpeakE DT *PAP	219	125	−1.5	82	51	−0.5	62	73	0.5	45	92
Sum Score of: E/ e’sept peakE DT *PAP	196	123	−1.5	66	63	−0.5	55	72	0.5	40	86
Score 2016	214	124	1.5	93	23	2.5	68	68	3.5	27	96

Score: sum of score for the three independent parameters <cutoff A = -1; between cut-off A and C: 0; ≥cut-off C = 1
DT Deceleration time, E Early diastolic transmitral flow velocity, e′ Early diastolic mitral annuler velocity, IVRT Isovolumic relaxation time, LA Left atrium, NT-proBNP N-terminal prohormone of brain natriuretic peptide, PAP Pulmonary artery pressure, PV SFF Pulmonary veins systolic filling fraction

ISSN: 1476-7120